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Synthesis, In Vitro and In Vivo Behaviour of TiO2 Containing Inorganic/Organic Hybrids

  • High-Performance Ceramics
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Interceram - International Ceramic Review

Abstract

In the present study inorganic/organic hybrids reinforced by introducing titanium (TiO2) in the form of Ti-n-butoxide were prepared. The phase composition, microstructure and mechanical properties of the prepared hybrids were investigated. Increasing the titanium content gradually enhanced the mechanical data of the prepared hybrids. The formation of apatite on the surface of the prepared hybrids was examined in SBF (simulated body fluid). In vivo studies revealed the ability of the hybrids to regenerate bone tissue in femur defects of adult male rabbits five months after surgery. The prepared hybrids are considered to be promising materials for bone substitutes or bone filler.

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Authors and Affiliations

  1. Department of Ceramics, National Research Center, Cairo, Egypt

    S. M. Naga & M. M. S. Wahsh

  2. Department of Biomaterials, National Research Center, Cairo, Egypt

    Abeer M. El-Kady

  3. Department of Physics, El Azhar University, Cairo, Egypt

    H. I. E. Asaker

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  1. S. M. Naga
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  2. M. M. S. Wahsh
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  3. Abeer M. El-Kady
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  4. H. I. E. Asaker
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Correspondence to S. M. Naga.

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Naga, S.M., Wahsh, M.M.S., El-Kady, A.M. et al. Synthesis, In Vitro and In Vivo Behaviour of TiO2 Containing Inorganic/Organic Hybrids. Interceram. - Int. Ceram. Rev. 64, 292–297 (2015). https://doi.org/10.1007/BF03401136

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  • DOI: https://doi.org/10.1007/BF03401136

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