Journal of Endocrinological Investigation

, Volume 8, Issue 1, pp 1–6 | Cite as

Corpus luteum function during the early puerperium

  • B. Cinque
  • M. I. Montesanti
  • E. Parlati
  • A. Lucisano
  • A. Montemurro
  • E. Maniccia
  • S. Dell’Acqua


Progesterone and 17β-estradiol peripheral plasma levels have been determined during labor and after 1,3,6,12,24,48,72,96,120 and 144 h from delivery in a group of 7 women, whose corpus luteum had been removed at delivery and in a corresponding control group with intact corpus luteum. In both groups the results indicate a progressive fall of progesterone and 17β-estradiol, that is evident until 144 h for progesterone and 72 h for 17β-estradiol. The analysis of the two groups with the Student’s t test has shown significantly lower levels in the group of women, whose corpus luteum had been removed, at the 6th h (p<0.01), 12th h (p<0.02) and 24th h (p < 0.05) for progesterone and at 3rd h (p < 0.01) and 6th (p < 0.01) for 17β-estradiol. The significant difference for progesterone appearing later than for 17β-estradiol could be due to the fact that progesterone is also dismissed by the adipose tissue, where it is stored. A further statistical elaboration of the results, carried out by calculating the regression line and the transfer function, confirmed the different pattern in time of progesterone and 17β-estradiol plasma levels after delivery in the two groups of patients considered.


Progesterone 17β-estradiol puerperium corpus luteum 


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Copyright information

© Italian Society of Endocrinology (SIE) 1985

Authors and Affiliations

  • B. Cinque
    • 1
  • M. I. Montesanti
    • 2
  • E. Parlati
    • 1
  • A. Lucisano
    • 1
  • A. Montemurro
    • 1
  • E. Maniccia
    • 1
  • S. Dell’Acqua
    • 1
  1. 1.Istituto di Clinica Ostetrica e GinecologicaUniversita Cattolica del S. CuoreRomaItaly
  2. 2.Istituto di Fisica MedicaUniversity “La Sapienza”RomaItaly

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