Journal of Endocrinological Investigation

, Volume 1, Issue 3, pp 259–261 | Cite as

Effect of hyperglycemia on the growth hormone response to L-dopa in diabetic subjects

  • A. Barbarino
  • L. De Marinis
  • F. Martino


Plasma growth hormone (GH) levels were measured before and after oral administration of L-dopa in 8 insulin-dependent juvenile diabetic patients, and in 6 non insulin-dependent maturity-onset diabetics, while they were hyperglycemic, and values were compared with those of normal children and adult subjects. Maturity-onset diabetics failed to show an increase in serum GH levels after L-dopa administration, while serum peak GH values of juvenile diabetic patients were not significantly different from those of normal adults and children. Hyperglycemia thus failed to prevent L-dopa induced growth hormone response in insulin-dependent juvenile diabetic patients.


Diabetes growth hormone hyperglycemia L-dopa 


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Copyright information

© Italian Society of Endocrinology (SIE) 1978

Authors and Affiliations

  • A. Barbarino
    • 1
    • 2
  • L. De Marinis
    • 1
    • 2
  • F. Martino
    • 1
    • 2
  1. 1.Division of EndocrinologyInstitute of Internal MedicineRomaItaly
  2. 2.Institute of Nuclear MedicineUniversità Cattolica del Sacro CuoreRomaItaly

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