Journal of Endocrinological Investigation

, Volume 12, Issue 9, pp 611–615 | Cite as

Evaluation of anterior pituitary function in hypertensive patients following inhibition of angiotensin II generation

  • S. Magna
  • P. Dessy-Fulgheri
  • A. Masala
  • P. Madeddu
  • P. P. Rovasio
  • N. Glorioso
  • A. Rappelli


The Authors investigated anterior pituitary function in hypertensive patients in basal conditions and following a 15-day course of treatment with Captopril, a drug which blocks the generation of Angiotensin II (Angio II). No differences were observed for any of the pituitary hormones except ACTH, whose response to hypoglycemia was significantly blunted by the pharmacological treatment. A possible role of Angio. II in modulating some aspects of pituitary function is proposed.


Anterior pituitary angiotensin II Captopril ACTH Cortisol 


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Copyright information

© Italian Society of Endocrinology (SIE) 1989

Authors and Affiliations

  • S. Magna
    • 1
  • P. Dessy-Fulgheri
    • 2
  • A. Masala
    • 1
  • P. Madeddu
    • 1
  • P. P. Rovasio
    • 1
  • N. Glorioso
    • 1
  • A. Rappelli
    • 2
  1. 1.Istituto di Patologia Speciale Medica e Metodologia ClinicaUniversity of SassariSassariItaly
  2. 2.Istituto di Patologia Speciale Medica e Metodologia ClinicaUniversity of AnconaAnconaItaly

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