Journal of Endocrinological Investigation

, Volume 18, Issue 10, pp 809–812 | Cite as

Ectopic aldosteronoma associated to another adrenocortical adenoma in the adrenal gland of the same side

  • E. Mazza
  • M. Papotti
  • R. Durando
  • A. Robecchi
  • Franco Camanni
Case Report


The occurrence of tumors originating from aberrant adrenocortical tissue in ectopic site is very rare. Up to now only two cases of ectopic aldosterone-producing adenoma have been described. We have observed another case of ectopic aldosteronoma, located in the retrocaval region, laterally to the body of the 12th thoracic vertebra. This ectopic tumor was associated to another adrenocortical adenoma, in the adrenal gland of the same side. The diagnostic implications of this observation are discussed.


Hyperaldosteronism choristoma adrenal gland neoplasms 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Arnold J., Mitchell A. Conn’s syndrome due to an ectopic adrenal adenoma. Postgrad. Med. J. 65: 847, 1989.PubMedCentralPubMedCrossRefGoogle Scholar
  2. 2.
    Flanagan M.J., McDonald J.H. Heterotopic adrenocortical adenoma producing primary aldosteronism. J. Urol. 98: 133, 1967.PubMedGoogle Scholar
  3. 3.
    Young W.F. Jr., Hogan M.J., Klee G.G., Grant C.S., van Heerden J.A. Primary aldosteronism: diagnosis and treatment. Mayo Clin. Proc. 65: 96, 1990.PubMedCrossRefGoogle Scholar
  4. 4.
    Jaffee H.L. The suprarenal gland. Arch. Pathol. Lab. Med. 3: 414, 1927.Google Scholar
  5. 5.
    Culp O.S. Adrenal heterotopia. A survery of the literature and a report of a case. J. Urol. 41: 303, 1939.Google Scholar
  6. 6.
    Schechter D.C. Aberrant adrenal tissue. Ann. Surg. 167: 421, 1968.PubMedCentralPubMedCrossRefGoogle Scholar
  7. 7.
    Goren E., Engelberg I.S., Eidelman A. Adrenal rest carcinoma in hilum of kidney. Urology 38: 187, 1991.PubMedCrossRefGoogle Scholar
  8. 8.
    Medeiros L.J., Anasti J., Gardner K.L., Pass H.I., Nieman L.K. Virilizing adrenal cortical neoplasm arising ectopically in the thorax. J. Clin. Endocrinol. Metab. 75: 1522, 1992.PubMedGoogle Scholar
  9. 9.
    Stein S.H., Latour F., Frost S.S. Myelolipoma arising from ectopic adrenal cortex: case report and review of the literature. Am. J. Gastroenterol. 81: 999, 1986.PubMedGoogle Scholar
  10. 10.
    Kageyama T., Doke Y., Takahashi M., Kaneko M. Computed tomography of myelolipoma in the accessory adrenal gland. Urol. Radiol. 11: 153, 1989.PubMedCrossRefGoogle Scholar
  11. 11.
    Nguyen G.K., Vriend R., Ronaghan D., Lakey W.H. Heterotopic adrenocortical oncocytoma. A case report with light and electron microscopic studies. Cancer 70: 2681, 1992.PubMedCrossRefGoogle Scholar
  12. 12.
    Lele S.M., Mittal B.V., Vora I.M., Kulkarni H.S. Nonfunctioning adrenocortical carcinoma. J. Postgrad. Med. 38: 145, 1992.PubMedGoogle Scholar
  13. 13.
    Harrison L.A. McMillan J.H., Batnitzky S., Kepes J.J. M.R. Appearance of an ectopic intraspinal adrenal cortical adenoma. A.J.N.R. Am. J. Neuroradiol. 11: 1185, 1990.Google Scholar
  14. 14.
    Kepes J.J., O’Boynick P., Jones S., Baum D., McMillan J., Adams M.E. Adrenal cortical adenoma in the spinal canal of an 8-year-old girl. Am. J. Surg. Pathol. 14: 481, 1990.PubMedCrossRefGoogle Scholar
  15. 15.
    Mitchell A., Scheithauer B.W., Sasano H., Hubbard E.W., Ebersold M.J. Symptomatic intradural adrenal adenoma of the spinal nerve root: report of two cases. Neurosurgery 32: 658, 1993.PubMedCrossRefGoogle Scholar
  16. 16.
    Seidenwurm D., Smathers R.L., Kan R., Hoffman A. Intratesticular adrenal rests diagnosed by ultrasound. Radiology 155: 479, 1985.PubMedGoogle Scholar
  17. 17.
    Burke E.F., Gilbert E., Uehling D.T. Adrenal rest tumors of the testis. J. Urol. 109: 649, 1973.PubMedGoogle Scholar
  18. 18.
    Ehrlich E.N., Dominguez O.V., Samuels L.T., Linch D., Oberhelman H. Jr., Warner N.E. Aldosteronism and precocious puberty due to an ovarian androblastoma (Sertoli cells tumor). J. Clin. Endocrinol. Metab. 23: 358, 1963.CrossRefGoogle Scholar
  19. 19.
    Todesco S., Terribile V. Borsatti A., Mantero F. Primary aldosteronism due to a malignant ovarian tumor. J. Clin. Endocrinol. Metab. 41: 809, 1975.PubMedCrossRefGoogle Scholar
  20. 20.
    Jakson B., Valentine R., Wagner G. Primary aldosteronism due to a malignant ovarian tumour. Aust. N.Z.J. Med. 16: 69, 1986.CrossRefGoogle Scholar
  21. 21.
    Sasano N., Sasano H. The adrenal cortex. In: Kovacs K., Asa S.L. (Eds.), Functional Endocrine Pathology. Blackwell Scientific Publications, Boston, 1991, p. 546.Google Scholar
  22. 22.
    Young F.W. Jr., Klee G.G. Primary aldosteronism. Diagnostic evaluation. In: Young F.W. Jr., Klee G.G. (Eds.), Diagnostic evaluation of endocrine disorders I. Endocrinol. Metab. North Am. Vol. 17, W.B. Saunders Company, Philadenphia, 1988, p. 367.Google Scholar
  23. 23.
    Kobayashi S., Seki T., Nonomura K., Gotoh T., Togashi M., Koyanagi T. Clinical experience of incidentally discovered adrenal tumor with particular reference to cortical function. J. Urol. 150: 8, 1993.PubMedGoogle Scholar
  24. 24.
    Aso Y., Homma Y. A survey on incidental adrenal tumors in Japan. J. Urol. 147: 1478, 1992.PubMedGoogle Scholar
  25. 25.
    Jockenhovel F., Kuck W., Hauffa B., Reinhardt W., Benker G., Lederbogen S., Olbricht T., Reinwein D. Conservative and surgical management of incidentally discovered adrenal tumors (incidentalomas). J. Endocrinol. Invest. 15: 331, 1992.PubMedCrossRefGoogle Scholar
  26. 26.
    Gross M.D., Shapiro B. Clinically silent adrenal masses. J. Clin. Endocrinol. Metab. 77: 885, 1993.PubMedGoogle Scholar

Copyright information

© Italian Society of Endocrinology (SIE) 1995

Authors and Affiliations

  • E. Mazza
    • 1
  • M. Papotti
    • 2
  • R. Durando
    • 3
  • A. Robecchi
    • 3
  • Franco Camanni
    • 1
  1. 1.Division of Endocrinology, Department of Clinical PathophysiologyItaly
  2. 2.Department of Biomedical Sciences and OncologyItaly
  3. 3.Division of SurgeryUniversity of TorinoItaly

Personalised recommendations