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Glucocorticoid-remediable aldosteronism

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References

  1. Sutherland D.J., Ruse J.L., Laidlaw J.C. Hypertension, increased aldosterone secretion and low plasma renin activity relieved by dexamethasone. Can. Med. Assoc. J. 95: 1109, 1966.

    CAS  PubMed Central  PubMed  Google Scholar 

  2. New M.I., Peterson R.E., et al. A new form of congenital adrenal hyperplasia. J. Clin. Endocrin. Metab. 27: 300, 1967.

    Article  CAS  Google Scholar 

  3. Fallo F., Mantero F. Dexamethasone-suppressible hyperaldosteronism. In: Biglieri E.G., Melby J.C. (Eds.), Endocrine Hypertension: Comprehensive Endocrinology, vol 57. Raven Press, New York 1990, p. 8797.

    Google Scholar 

  4. Williams G.H., Dluhy R.G. Diseases of the adrenal cortex. In: Isselbacher K. et al (Eds.). Harrison’s Principles of Internal Medicine, ed. 13. MacGraw-Hill Book Company, New York, 1994, p. 1953.

    Google Scholar 

  5. Rich G.M., Ulick S., Cook S., et al. Glucocorticoid-remediable aldosteronism in a large kindred: Clinical spectrum and diagnosis using a characteristics biochemical phenotype. Ann. Int. Med. 116: 813, 1992.

    Article  CAS  PubMed  Google Scholar 

  6. Fallo F., Sonino N., Armanini D., et al. A new family with dexamethasone-suppressibie hyperaldosteronism: Aldosterone unresponsiveness to angiotensin II. Clin. Endocrinol. 22: 777, 1985.

    Article  CAS  Google Scholar 

  7. Grim C., Weinberger M., et al. Familial dexamethasone-suppressible normokaiemic hyperaldosteronism. Pediatrics 65: 597, 1980.

    CAS  PubMed  Google Scholar 

  8. Chu M.D., Ulick S.J., et al. Isolation and identification of 18-hydroxycortisol from the urine of patients with primary aldosteronism. J. Biol. Chem. 257: 2218, 1982.

    CAS  PubMed  Google Scholar 

  9. Ganguly A., Weinberg M., Guthrie G.P., et al. Adrenal steroid response to ACTH in glucocorticoid-suppressible hyperaldosteronism. Hypertension 6: 563, 1984.

    Article  CAS  PubMed  Google Scholar 

  10. Giebink G.S., Gotlin R.W., Biglieri E.G., et al. A kindred with familial glucocorticoid-suppressible hyperaldosteronism. J. Clin. Endocrin. Metab. 36: 715, 1973.

    Article  CAS  Google Scholar 

  11. New M.I., Siegal E.J., Peterson R.E.: Dexamethasone-suppressible hyperaldosteronism. J Clin Endocrin Metab 37: 93–100, 1973

    Article  CAS  Google Scholar 

  12. Ganguly A., Grim C., Weinberger M. Anomalous postural response in glucocorticoid-suppressible hyperaldosteronism. N Engl J Med 305: 991–993, 1981

    Article  CAS  PubMed  Google Scholar 

  13. Oberfield S.E., Levine L.S., Stoner E., et al. Adrenal glomerulosa function in patients with dexamethasone-suppressible hyperaldosteronism. J. Clin. Endocrinol. Metab. 53: 158, 1981.

    Article  CAS  PubMed  Google Scholar 

  14. Woodland E., Tunny T.J., Hamlet S.M., et al. Hypertension corrected and aldosterone responsiveness to renin-angiotensin restored by long-term dexamethasone in glucocorticoid-suppressible hyperaldosteronism. Clin. Exp. Pharmacol. Physiol. 12: 245, 1985.

    Article  CAS  PubMed  Google Scholar 

  15. Spence C.D., Coghlan J.P., Denton D.A., et al. Blood pressure and metabolic effects of 18-oxo-cortisol in sheep. J. Steroid. Biochem. 28: 441, 1987.

    Article  CAS  PubMed  Google Scholar 

  16. Gomez-Sanchez C., Gomez-Sanchez E.P., Smith J.S. Receptor binding and biological activity of 18-oxocortisol. Endocrinology 116: 6, 1985.

    Article  CAS  PubMed  Google Scholar 

  17. Chua S.C., Szabo P., Vitek A., et al. Cloning of cDNA encoding steroid 11-hydroxylase (P-450c11). Proc Natl Acad Sci USA 84: 7193, 1987.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  18. Kawamoto T., Mitsuuchi Y., Ohnishi T. et al: Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism. Biochem. Biophys. Res. Commun. 173: 309, 1990.

    Article  CAS  Google Scholar 

  19. Mornet E., Dupont B., Vitek A., et al. Characterization of two genes encoding human steroid 11 hydroxylase (P-450c11). J. Biol.Chem. 264: 961, 1989.

    Google Scholar 

  20. Ogishima T., Shibata H., Shimada H., et al. Aldosterone synthase cytochrome P-450 expressed in the adrenals of patients with primary aldosteronism. J Biol. Chem. 266: 731, 1991.

    Google Scholar 

  21. Lifton R.P., Dluhy R.G., Powers M., et al. A chimeric 11-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature 355: 262, 1992.

    Article  CAS  PubMed  Google Scholar 

  22. Lifton R.P., Dluhy R.G., Powers M., et al. Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase. Nature Genet. 2: 66, 1992.

    Article  CAS  PubMed  Google Scholar 

  23. Pascoe L., Curnow K.M., Slutsker L., et al. Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2. Proc. Natl. Acad. Sci. USA 89: 8327, 1992.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  24. Stockigt J.R., Scoggins B.A., et al. Long-term evolution of glucocorticoid-suppressible hyperaldosteronism. J. Clin. Endocrin. Metab. 64: 22, 1987.

    Article  CAS  Google Scholar 

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Williams, G.H., Dluhy, R.G. Glucocorticoid-remediable aldosteronism. J Endocrinol Invest 18, 512–517 (1995). https://doi.org/10.1007/BF03349762

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