Study of an endemic goiter area in northern Campania
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The purpose of this paper was the determination, in the endemic goiter area of Teano (Caserta, Italy), of: i) The goiter prevalence in a group of 920 patients who attended the Outpatient Endocrinology Department; ii) The urinary iodine excretion in 150 adults (20–73-year-old) and 502 children (10–16-year- old); iii) The thyroid size in the 502 children; iv) The environmental iodine levels. Out of 920 patients a total of 750 (81.5%) goiters were detected. Out of these 750 cases, 415 (55.3%) were of grades 1b and 2, 335 (44.7%) of grades 3 and 4. A statistically significant association between goiter size and age was found (p < 0.05). Laboratory data were entirely available for 506 goitrous patients. Serum TG levels was increased with goiter size and age, whereas there was a progressive decrease in mean serum TSH levels with increasing goiter size and age. The screening program performed on 502 schoolchildren aged 10 to 16 yr found a 68.3% prevalence of grade 1 goiter and a mean urinary ratio iodine/creatinine of 52 ± 32 (SD) μ/g. A mean urinary ratio iodine/creatinine of 60 ± 27 (SD) μ/g was reported in a sample of 150 adult inhabitants. Iodine measurements in water supplies showed levels equal to or less than 1 μg/l. The area investigated can be identified as a moderate iodine deficient area and classified as grade 1–2 according to the Pan American Health Organization criteria.
KeywordsGoiter Iodine Deficiency Lodine Thyroid Volume Nodular Goiter
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