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Journal of Endocrinological Investigation

, Volume 3, Issue 1, pp 59–61 | Cite as

Response of insulin receptors to oral glucose in normal subjects

  • Aldo Bertoli
  • R. De Pirro
  • A. V. Greco
  • A. Fusco
  • L. Spallone
  • G. Ghirlanda
  • R. Lauro
Comment

Abstract

Insulin binding to circulating monocytes was studied in ten male volunteers before and 1, 2, and 5 hours after the oral intake of 100 g of glucose. Results indicate an increase in the specific cell binding fraction with a change in receptor affinity 5 hours after glucose. Since the same changes appear 3 hours after food intake they are probably not directly induced by insulinemia.

Key-words

Insulin insulin binding insulin receptor oral glucose tolerance test monocytes 

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Copyright information

© Italian Society of Endocrinology (SIE) 1978

Authors and Affiliations

  • Aldo Bertoli
    • 1
  • R. De Pirro
    • 2
  • A. V. Greco
    • 1
  • A. Fusco
    • 1
  • L. Spallone
    • 2
  • G. Ghirlanda
    • 1
  • R. Lauro
    • 2
  1. 1.Istituto di Patologia MedicaUniversità Cattolica del Sacro CuoreRomaItaly
  2. 2.2a Clinica MedicaUniversità di RomaRomaItaly

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