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Journal of Endocrinological Investigation

, Volume 26, Issue 7, pp 679–682 | Cite as

Coexistence of a parathyroid adenoma and parathyroid cyst causing primary hyperparathyroidism

  • G. Ardito
  • G. Fadda
  • D. Danese
  • Pietro Modugno
  • A. Giordano
  • L. Revelli
  • F. Ardito
  • A. Pontecorvi
Case Report

Abstract

The association of a functional parathyroid cyst with a parathyroid adenoma is an uncommon finding. In this report we describe the clinical history of a 60-yr-old man, presenting with the following findings: hypercalcemia (18.9 mg/dl), elevated serum parathormone levels (1320 pg/dl), hypercalciuria (228 mg/dl), and hyperphosphaturia (155 mg/dl). Neck ultrasound, magnetic resonance imaging (MRI) and 99Tc Sestamibi scintigraphy led to the identification of a left parathyroid adenoma, located at the lower pole of the left thyroid gland lobe, associated with a parathyroid cyst, located at the upper extremity of the same thyroid lobe. Parathyroidectomy was performed and the histological examination confirmed the diagnosis of a parathyroid adenoma with aspects of cystic degeneration and an upper parathyroid cyst. Analysis of the cristal clear intracystic fluid showed elevated parathyroid hormone (PTH) levels (137.000 pg/ml). The patient is normocalcemic at 2 yr after surgery without signs of recurrent parathyroid enlargements. Aetiology, diagnosis and management of parathyroid cyst will be discussed.

Key-words

Hyperparathyroidism parathyroid adenoma parathyroid cyst 

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Copyright information

© Italian Society of Endocrinology (SIE) 2003

Authors and Affiliations

  • G. Ardito
    • 1
  • G. Fadda
    • 2
  • D. Danese
    • 3
  • Pietro Modugno
    • 1
  • A. Giordano
    • 4
  • L. Revelli
    • 1
  • F. Ardito
    • 1
  • A. Pontecorvi
    • 5
  1. 1.Institute of Surgical SemeiothicCatholic University of Sacred HeartRomeItaly
  2. 2.Institute of Pathological AnatomyCatholic University of Sacred HeartRomeItaly
  3. 3.Service of EndocrinologyItalian Air Force Health ServiceRomeItaly
  4. 4.Institute of Radiology - Service of Nuclear MedicineRomeItaly
  5. 5.Institute of Medical PathologyCatholic University of Sacred Heart and Molecular Oncogenesis Laboratory, Regina Elena Cancer InstituteRomeItaly

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