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Journal of Endocrinological Investigation

, Volume 34, Issue 1, pp 60–64 | Cite as

Assessment of the awareness and management of sleep apnea syndrome in acromegaly. The COM.E.TA (Comorbidities Evaluation and Treatment in Acromegaly) Italian Study Group

  • E. De Menis
  • A. Giustina
  • A. Colao
  • E. Degli Uberti
  • E. Ghigo
  • F. Minuto
  • F. Bogazzi
  • R. Drigo
  • A. Cattaneo
  • G. Aimaretti
  • COM.E.T.A. (COMorbidities Evaluation and Treatment in Acromegaly) Italian Study Group
Original Articles

Abstract

In 2007 the Italian COM.E.T.A. (COMorbidities Evaluation and Treatment in Acromegaly) study group started to assess the application in a clinical setting of the Versailles criteria for management of acromegaly complications by a first questionnaire focusing on cardiovascular co-morbidities. A further questionnaire on sleep apnea syndrome (SAS) was delivered by the COM.E.T.A. study group to 107 endocrine centers in Italy. The results of our survey suggest that SAS is a well-known comorbidity even if its estimated prevalence is lower than in the literature. Polysomnography is the preferred tool for diagnosis. Control of SAS is considered relevant both for quality of life and co-morbidities. Continuous positive airway pressure is the cornerstone of therapy, but patients’ acceptance may be critical. Control of GH/IGF-I secretion is important to improve SAS. Management of SAS requires cooperation between specialists.

Keywords

Acromegaly sleep apnea syndrome somatostatin analogs 

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Copyright information

© Italian Society of Endocrinology (SIE) 2011

Authors and Affiliations

  • E. De Menis
    • 1
  • A. Giustina
    • 2
  • A. Colao
    • 3
  • E. Degli Uberti
    • 4
  • E. Ghigo
    • 5
  • F. Minuto
    • 6
  • F. Bogazzi
    • 7
  • R. Drigo
    • 8
  • A. Cattaneo
    • 9
  • G. Aimaretti
    • 10
  • COM.E.T.A. (COMorbidities Evaluation and Treatment in Acromegaly) Italian Study Group
  1. 1.Department of Internal MedicineGeneral HospitalMontebellunaItaly
  2. 2.University of BresciaBresciaItaly
  3. 3.University of NaplesNaplesItaly
  4. 4.University of FerraraFerraraItaly
  5. 5.University of TurinTurinItaly
  6. 6.University of GenovaGenovaItaly
  7. 7.University of PisaPisaItaly
  8. 8.General HospitalFeltreItaly
  9. 9.Ipsen S.p.a.Italy
  10. 10.University “A. Avogadro” of Piemonte OrientaleNovaraItaly

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