Advertisement

L’Endocrinologo

, Volume 13, Issue 3, pp 132–136 | Cite as

Disturbi del sonno e sindrome metabolica: quali relazioni eziopatogenetiche?

Proposto da Emanuela Arvat
  • Valentina Ramella Gigliardi
  • Elena Gramaglia
  • Michela Tomelini
  • Ilaria Olivetti
  • Andrea Benso
  • Elisa Calvi
  • Stefano Frara
  • Ezio Ghigo
  • Fabio Broglio
Article
  • 29 Downloads

Riassunto

Nelle ultime decadi si è assistito a un incremento dell’incidenza dei disturbi quali-quantitativi del sonno. Parallelamente è aumentata l’incidenza della sindrome metabolica. Quest’ultimo fenomeno è certamente imputabile in primo luogo a fattori ambientali (iper-alimentazione e sedentarietà) ma numerose evidenze epidemiologiche e sperimentali suggeriscono che i disturbi del sonno possano agire come concausa. Del resto un sonno quantitativamente e qualitativamente adeguato è fondamentale per il mantenimento di un ottimale metabolismo glicidico, dell’integrità dei meccanismi di regolazione dell’appetito e di un normale pattern pressorio. La consapevolezza di una possibile associazione tra i disturbi del sonno e le diverse componenti della sindrome metabolica offre importanti spunti nel campo della prevenzione e del trattamento di queste ultime.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Bibliografia

  1. 1.
    Van Cauter E, Spiegel K, Tasali E, Leproult R 2008 Metabolic consequences of sleep and sleep loss. Sleep Medicine 9 Suppl 1:S23–S28.PubMedCrossRefGoogle Scholar
  2. 2.
    Wolk R, Somers VK 2007 Sleep and metabolic syndrome. Exp Physiol 92:67–78.PubMedCrossRefGoogle Scholar
  3. 3.
    Knutson KL, Spiegel K, Penev P, Van Cauter E 2007 The metabolic consequences of sleep deprivation. Sleep Med Rev 11:163–178.PubMedCentralPubMedCrossRefGoogle Scholar
  4. 4.
    Spiegel K, Tasali E, Leproult R, Van Cauter E 2009 Effects of poor and short sleep on glucose metabolism and obesity risk. Nat Rev Endocrinol 5:253–261.PubMedCrossRefGoogle Scholar
  5. 5.
    Knutson KL, Van Cauter E 2008 Associations between sleep loss and increased risk of obesity and diabetes. Ann N Y Acad Sci 1129: 287–304.PubMedCrossRefGoogle Scholar
  6. 6.
    Meier-Ewert HK, Ridker PM, Rifai N 2004 Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk. J Am Coll Cardiol 43:678–683.PubMedCrossRefGoogle Scholar
  7. 7.
    Cappuccio FP, Taggart FM, Kandala NB, Currie A, Peile E, Stranges S, Miller MA 2008 Meta analysis on short sleep duration and obesity in children and adults. Sleep 31:619–626.PubMedCentralPubMedGoogle Scholar
  8. 8.
    Chen X, Beydoun MA, Wang Y 2008 Is sleep duration associated with childhood obesity?. Obesity (Silver Spring) 16:265–274.CrossRefGoogle Scholar
  9. 9.
    Smolensky MH, Hermida RC, Castriotta RJ, Portaluppi F 2007 Role of sleep-wake cycle on blood pressure circadian rhythms and hypertension. Sleep Med 8:668–680.PubMedCrossRefGoogle Scholar
  10. 10.
    Gangwisch JE, Heymsfield SB, Boden-Albala B, Buijs RM, Kreier F, Pickering TG, Rundle AG, Zammit GK, Malaspina D 2006 Short sleep duration as a risk factor for hypertension. Analyses of the First National Health and Nutrition Examination Survey. Hypertension 47:833–839.PubMedCrossRefGoogle Scholar
  11. 11.
    Nagai M, Hoshide S, Kario K 2010 Sleep duration as a risk factor for cardiovascular disease — a review of the recent literature. Curr Cardiol Rev 6:54–61.PubMedCentralPubMedCrossRefGoogle Scholar
  12. 12.
    Lam JCM, Ip MSM 2010 Sleep and the metabolic syndrome. Indian J Med Res 131:206216.Google Scholar
  13. 13.
    Drager LF, Jun JC, Polotsky VY 2010 Metabolic consequences of intermittent hypoxia: relevance to obstructive sleep apnea. Best Pract Res Clin Endocrinol Metab 24:843–851.PubMedCentralPubMedCrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG 2012

Authors and Affiliations

  • Valentina Ramella Gigliardi
    • 1
  • Elena Gramaglia
    • 1
  • Michela Tomelini
    • 1
  • Ilaria Olivetti
    • 1
  • Andrea Benso
    • 1
  • Elisa Calvi
    • 1
  • Stefano Frara
    • 1
  • Ezio Ghigo
    • 1
  • Fabio Broglio
    • 1
  1. 1.Divisione di Endocrinologia, Diabetologia e MetabolismoUniversità di Torino, A. O. U. S. Giovanni BattistaTorinoItalia

Personalised recommendations