Abstract
The tissue distribution of the membrane receptor for the Sex Steroid Binding Protein (SBP) has been studied, either in estrogen/androgen dependent tissues and in tissues not strictly sex steroid dependent. A specific interaction of SBP with cell mem-branes has been observed to occur only in estro gen/androgen dependent tissues, some of them had been previously shown by our laboratory and by other authors to possess a specific receptor for the protein. Thus, the sex steroid dependence of the tissue is likely to be determinant for the expression of the membrane receptor for Sex Steroid Binding Protein.
References
Hryb D.J., Khan M.S., Rosner W. Testosterone-estradiol binding globulin binds to human prostate cell membranes. Biochem. Biophys. Res. Commun. 128: 432, 1985.
Strel’chyonok O.A., Avvakumov G.V., Survilo L.I. A recognition system for sex hormone binding protein-estradiol complex in human decidual endometrium plasma membranes. Biochem. Biophys. Res. Commun. 802: 459, 1984.
Krupenko N.T., Avvakumov G.V., Strel’chyonok O.A. Binding of human sex hormone binding globulin-androgen complexes to the placental syncytiotro-phoblast membrane. Biochem. Biophys. Res. Commun. 71: 1279, 1990.
Fortunati N., Fissore F., Fazzari A., Berta L., Giudici M., Frairia R. Sex steroid binding protein interacts with a specific receptor on human pre-menopauaal endometrium membrane: modulating effect of estradiol. Steroids 56: 341, 1991.
Fortunati N., Frairia R., Fissore F., Berta L., Fazzari A., Gaidano G. The receptor for human sex steroid binding protein (SBP) is.expressed on membranes of neoplastic endometrium. J. Steroid. Biochem. Molec. Biol. 42: 185, 1992.
Rosner W. The functions of corticosteroid binding globulin and sex hormone binding globulin: recent advances. Endocr. Rev. 11: 80, 1990.
Strel’chyonok O.A., Avvakumov G.V. Specific steroid-binding glycoproteins of human blood plasma: novel data on their structure and function. J. Steroid Biochem. 35: 519, 1990.
Bolton A.E., Hunter W.M. The labelling of proteins to high specific radioactivity by conjugation to a 125I containing acylating agent. Biochem. J. 133: 529, 1973.
Fernlund P., Gershagen S., Larsson I., Rannevik G. Radioimmunoassay of human sex hormone binding globulin: improved radioiodination procedure. Scand. J. Clin. Lab. Invest. 45: 461, 1985.
Laemli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680, 1970.
Singer C.J., Khan M.S., Rosner W. Characterisation of the binding of corticosteroid binding globulin to rat cell membranes. Endocrinology 122: 89, 1988.
Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248, 1976.
Aronson N., Touster O. Isolation of rat liver plasma membrane fragments in isotonic sucrose. Methods Enzymol. 31: 90, 1974.
Hryb D.J., Khan M.S., Romas N.A., Rosner W.
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Frairia, R., Fortunati, N., Fissore, F. et al. The membrane receptor for sex steroid binding protein is not ubiquitous. J Endocrinol Invest 15, 617–619 (1992). https://doi.org/10.1007/BF03344935
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DOI: https://doi.org/10.1007/BF03344935