Journal of Endocrinological Investigation

, Volume 23, Issue 8, pp 515–519 | Cite as

Prevalence of the sleep apnea syndrome in acromegaly population

  • V. Weiss
  • K. Šonka
  • M. Pretl
  • S. Dostálová
  • J. Klozar
  • P. Rambousek
  • J. Marek
  • T. Haas
Original Article


The prevalence of sleep apnea syndrome (SAS) in acromegaly is high. Consequences of SAS are serious and are associated with increased morbidity and mortality. The aim of this study was to assess the relative frequency and predictive factors for SAS in a group of patients with acromegaly (n=55). The presence of SAS was evaluated using the Polymesam device. Hormonal and clinical examination consisted of assessment of growth hormone, insulin-like growth factor I plasma levels, body mass index (BMI), neck circumference, age, sex, treatment modes of acromegaly and ear, nose and throat (ENT) examination. The relative frequency of SAS in our group of patients with acromegaly was 75%. Independent predictors of SAS were: increased activity of acromegaly, higher age and neck circumference. No association between SAS and BMI and ENT findings was observed. The role of gender was controversial.


Sleep apnea syndrome acromegaly Polymesam upper airway obstruction central apnea 


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Copyright information

© Italian Society of Endocrinology (SIE) 2000

Authors and Affiliations

  • V. Weiss
    • 1
  • K. Šonka
    • 2
  • M. Pretl
    • 2
  • S. Dostálová
    • 2
  • J. Klozar
    • 3
  • P. Rambousek
    • 3
  • J. Marek
    • 1
  • T. Haas
    • 1
  1. 1.III Dept of Internal Medicine of the 1st Medical FacultyCharles UniversityPraha 2Czech Republic
  2. 2.Department of Neurology, 1st Medical FacultyCharles UniversityPragueCzech Republic
  3. 3.Department of Otorhinolaryngology, 2nd Medical FacultyCharles UniversityPragueCzech Republic

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