Aging Clinical and Experimental Research

, Volume 6, Issue 5, pp 307–321 | Cite as

Studies of the epidemiology of dementia: Comparisons between developed and developing countries

  • V. Chandra
  • Mary Ganguli
  • G. Ratcliff
  • R. Pandav
  • S. Sharma
  • J. Gilby
  • S. Belle
  • C. Ryan
  • C. Baker
  • E. Seaberg
  • S. DeKosky
  • L. Nath
Special Article


By the year 2025, 68% of the world’s population aged 65 and above, nearly 277 million people, will be residing in developing countries. The less industrialized nations have been the least studied to date, and may yield significant new information about the etiology and risk factors for Alzheimer’s disease (AD) and other dementias. Although it is readily apparent that cross- national and cross- cultural comparisons are desirable, these can be meaningful only if based on comparable methodology. In this work we will discuss some general conceptual and methodological issues regarding epidemiological studies of dementia in developing countries. The topics discussed include community- based screening for dementia, screening instruments and their application in cross- cultural studies, steps in standardization of new or modified neuropsychological tests, and some special considerations in studying uneducated/illiterate populations. (Aging Clin. Exp. Res. 6: 307- 321, 1994)


Alzheimer’s disease dementia developing countries epidemiology 


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Copyright information

© Springer Internal Publishing Switzerland 1994

Authors and Affiliations

  • V. Chandra
    • 1
    • 2
    • 5
  • Mary Ganguli
    • 4
    • 5
  • G. Ratcliff
    • 4
    • 8
  • R. Pandav
    • 1
  • S. Sharma
    • 1
  • J. Gilby
    • 4
  • S. Belle
    • 5
    • 7
  • C. Ryan
    • 4
  • C. Baker
    • 6
  • E. Seaberg
    • 5
  • S. DeKosky
    • 4
  • L. Nath
    • 3
  1. 1.Centre for Ageing Research in IndiaNew Delhi
  2. 2.Holy Family HospitalNew Delhi
  3. 3.Centre for Community MedicineAll India Institute of Medical SciencesNew DelhiIndia
  4. 4.Department of PsychiatryUniversity of Pittsburgh, School of MedicineUSA
  5. 5.Graduate School of Public HealthUSA
  6. 6.Office of Measurement and Evaluation, and School of EducationUSA
  7. 7.School of NursingPittsburgh
  8. 8.Harmarville Rehabilitation CenterPittsburghUSA

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