Aging Clinical and Experimental Research

, Volume 2, Issue 2, pp 207–215 | Cite as

Establishing diagnostic criteria for a registry for dementing diseases

  • John C. Morris
Reports From the National Institute on Aging Methods and problems in the development of registries for dementing diseases of later life UNIT II

Key Words

Alzheimer’s disease vascular dementia diagnostic accuracy clinical assessment dementia registry 


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  1. 1.
    Rocca W.A., Amaducci L.A., Schoenberg B.S.: Epidemiology of clinically diagnosed Alzheimer’s disease. Ann. Neurol 19: 415–424, 1986.PubMedCrossRefGoogle Scholar
  2. 2.
    Neumann M.A., Cohn R.: Neuropathologic data in Alzheimer’s disease. Arch. Neurol 40: 830, 1983.PubMedCrossRefGoogle Scholar
  3. 3.
    Alafuzoff I., Iqbal K., Fiden H., Adolfsson R., Winblad B.: Histopathological criteria for progressive dementia disorders: clinical-pathological correlation and classification by multivariate data analysis. Acta. Neuropathol. (Bed) 74: 209–225, 1987.CrossRefGoogle Scholar
  4. 4.
    Berg L.: Does Alzheimer’s disease represent an exaggeration of normal aging? Arch. Neurol. 42: 737–739, 1985.Google Scholar
  5. 5.
    Brayne C., Calloway P.: Normal aging, impairing cognitive function, and senile dementia of the Alzheimer’s type: a continuum? Lancet I: 1265–1267, 1988.CrossRefGoogle Scholar
  6. 6.
    Differential Diagnosis of Dementing Diseases. Dementia Consensus Conference. JAMA 258: 3411–3416, 1987.CrossRefGoogle Scholar
  7. 7.
    Khachaturian Z.S.: Diagnosis of Alzheimer’s disease. Arch. Neurol 42: 1097–1105, 1985.PubMedCrossRefGoogle Scholar
  8. 8.
    Wisniewski K., Jervis G.A., Moretz R.C., Wisniewski H.M.: Alzheimer’s neurofibrillary tangles in diseases other than senile and presenile dementia. Ann. Neurol. 5: 288–290, 1979.PubMedCrossRefGoogle Scholar
  9. 9.
    Blessed G., Tomlinson B.E., Roth M.: The association between quantitative measures of dementia and senile change in the cerebral grey matter of elderly subjects. Br. J. Psychiatry 114: 797–811, 1968.PubMedCrossRefGoogle Scholar
  10. 10.
    McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M.: Clinical diagnosis of Alzheimer’s disease: Report of the NINCDSADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s disease. Neurology 34: 939–944, 1984.PubMedCrossRefGoogle Scholar
  11. 11.
    American Psychiatric Association, Division of Public Affairs: Diagnostic and Statistical Manual of Mental Disorders, ed. 3. DSM-III, Washington, 1980, pp. 107-128.Google Scholar
  12. 12.
    Gurland B.J.: The borderlands of dementia: the influence of sociocultural characteristics on rates of dementia occurring in the senium. In: Miller N.E., Cohen G.D. (Eds.), Aging Series Vol. 15, Clinical Aspects of Alzheimer’s Disease and Senile Dementia, Raven Press, New York, 1981, pp. 61–84.Google Scholar
  13. 13.
    Escobar J.I., Burnham A., Karno M., Forsythe A., Landsver K.J., Golding J.M.: Use of the Mini-Mental State Examination (MMSE) in a community of mixed ethnicity: cultural and linguistic artifacts. J. New. Ment. Dis. 174: 607–614,1986.CrossRefGoogle Scholar
  14. 14.
    Anthony J.C., LeResche L., Niaz U., Von Rorff M.R., Folstein M.F.: Limits of the “Mini-Mental State” as a screening test for dementia and delirium among hospital patients. Psychol. Med. 12: 397–408, 1982.PubMedCrossRefGoogle Scholar
  15. 15.
    Dalton J.E., Pederson S.L., Blom B.E., Holmes N.R.: Diagnostic errors using the short portable mental status questionnaire with a mixed clinical population. J. Gerontol 42: 512–514,1987.PubMedCrossRefGoogle Scholar
  16. 16.
    Little A., Hensley D., Volans J.: Comparison of current levels of performance and scores based on change as diagnostic discriminators among the elderly. Br. J. Clin. Psychol. 26: 135–140, 1987.PubMedCrossRefGoogle Scholar
  17. 17.
    Roth M., Tym E., Mountjoy C.Q., Huppert F.A., Hendrie H., Verma S., Goddard R.: CAMDEX: a standardized instrument for the diagnosis of mental disorder in the elderly with special reference to the elderly detection of dementia. Br. J. Psychiatry 149: 698–709, 1986.PubMedCrossRefGoogle Scholar
  18. 18.
    Kaszniak A.W.: Cognition in Alzheimer’s disease: Theoretic models and clinical implications. Neurobiol. Aging 9: 92–94, 1988.PubMedCrossRefGoogle Scholar
  19. 19.
    Huppert F.A., Tym E.: Clinical and neuropsychological assessment of dementia. Br. Med. Bull. 42: 11–18, 1986.PubMedGoogle Scholar
  20. 20.
    Jorm A.F., Korten A.E.: Assessment of cognitive decline in the elderly by informant interview. Br. J. Psychiatry 152: 209–213, 1988.PubMedCrossRefGoogle Scholar
  21. 21.
    Tierney M.C., Fisher R.H., Lewis A.J., Zorzitto M.L., Snow W.G., Reid D.W., Nieuwstraten P.: The NINCDS-ADRD A Work Group criteria for the clinical diagnosis of probable Alzheimer’s disease: a clinico- pathologic study of 57 cases. Neurology 38: 359–364, 1988.PubMedCrossRefGoogle Scholar
  22. 22.
    Tomlinson B.E., Blessed G., Roth M.: Observations on the brains of non-demented old people. J. Neurol. Sei. 7: 331–356,1968.CrossRefGoogle Scholar
  23. 23.
    Brust J.C.M.: Vascular dementia still overdiagnosed. Stroke 14: 298–300, 1983.PubMedCrossRefGoogle Scholar
  24. 24.
    Molsa P.K., Paljarvi L., Rinne J.O., Rinne V.K., Säkö E.: Validity of clinical diagnosis in dementia: a prospective clinicopathological study. J. Neurol. Neurosurg. Psychiatry 48: 1085–1090, 1985.PubMedCrossRefGoogle Scholar
  25. 25.
    Wade J.P.H., Mirsen T.R., Hachinski V.C., Fisman M., Lau C., Merskey H.: The clinical diagnosis of Alzheimer’s disease. Arch. Neurol. 44: 24–29, 1987.PubMedCrossRefGoogle Scholar
  26. 26.
    Inzitari D., Diaz F., Fox A., Hachinski V.C., Steingart A., Lau C., Donald A., Wade J., Mulic H., Merskey H.: Vascular risk factors and leukoaraiosis. Arch. Neurol. 44: 42–47, 1987.PubMedCrossRefGoogle Scholar
  27. 27.
    Roman G.C.: Senile dementia of the Binswanger type: a vascular form of dementia in the elderly. JAMA 258: 1782–1788, 1987.PubMedCrossRefGoogle Scholar
  28. 28.
    Rezek D.L., Morris J.C., Fulling K.H., Gado M.H.: Periventricular white matter lucencies in senile dementia of the Alzheimer’s type and in normal aging. Neurology 37: 1365–1368, 1987.PubMedCrossRefGoogle Scholar
  29. 29.
    Johnson K.A., Davis K.R., Buonanno F.S., Brady T.J., Rosen T.J., Growdon J.H.: Comparison of magnetic resonance and Roentgen ray computed tomography in dementia. Arch. Neurol. 44: 1075–1080, 1987.PubMedCrossRefGoogle Scholar
  30. 30.
    O’Brien M.D.: Vascular dementia is underdiagnosed. Arch. Neurol. 45: 797–798, 1988.PubMedCrossRefGoogle Scholar
  31. 31.
    Brust J.C.M.: Vascular dementia is overdiagnosed. Arch. Neurol. 45: 799–801, 1988.PubMedCrossRefGoogle Scholar
  32. 32.
    Joynt R.J.: Vascular dementia: too much, or too little? Arch. Neurol. 45: 801, 1988.Google Scholar
  33. 33.
    Larson E.B., Reifler B.V., Sumi S.M., Canfield C.G., Chinn N.M.: Diagnostic tests in the evaluation of dementia: a prospective study of 200 elderly outpatients. Arch. Intern. Med. 146: 1917–1922,1986.PubMedCrossRefGoogle Scholar
  34. 34.
    Larson E.B., Kukull W.A., Buchner D., Reifler B.V.: Adverse drug reactions associated with global cognitive impairment in elderly persons. Ann. Intern. Med. 107: 169–173, 1987.PubMedCrossRefGoogle Scholar
  35. 35.
    Nott P.N., Fleminger J.J.: Presenile dementia: the difficulties of early diagnosis. Acta Psychiatr. Scand. 51: 210–217, 1975.PubMedCrossRefGoogle Scholar
  36. 36.
    Henderson A.S., Huppert F.A.: The problem of mild dementia. Psychol. Med. 14: 5–11,1984.PubMedCrossRefGoogle Scholar
  37. 37.
    Cooper B., Bickel H.: Population screening and the early detection of dementing disorders in old age: a review. Psychol. Med. 14: 81–95, 1984.PubMedCrossRefGoogle Scholar
  38. 38.
    Pfeffer R.I., Afifi A.A., Chance J.M.: Prevalence of Alzheimer’s disease in a retirement community. Am. J. Epidemiol. 125: 420–436, 1987.PubMedGoogle Scholar
  39. 39.
    Berg L., Hughes C.P., Coben L.A., Danziger W.L., Martin R.L., Knesevich J.: Mild senile dementia of the Alzheimer’s type: research diagnostic criteria, recruitment, and description of a study population. J. Neurol. Neurosurg. Psychiatry 45: 962–968, 1982.PubMedCrossRefGoogle Scholar
  40. 40.
    Hughes C.P., Berg L., Danziger W., Coben L.A., Martin R.L.: A new clinical scale for the staging of dementia. Br. J. Psychiatry 140: 566–572, 1982.PubMedCrossRefGoogle Scholar
  41. 41.
    Berg L.: Mild senile dementia of the Alzheimer’s type: diagnostic criteria and natural history. Mt. Sinai J. Med. 55: 87–96,1988.PubMedGoogle Scholar
  42. 42.
    Burke W.J., Miller J.P., Rubin E.H., Morris J.C., Coben L.A., Duchek J., Wittels I.G., Berg L.: The reliability of the Washington University Clinical Dementia Rating (CDR). Arch. Neurol. 45: 31–32,1988.PubMedCrossRefGoogle Scholar
  43. 43.
    Morris J.C., McKeel D.W.Jr., Fulling K., Torack R.M., Berg L.: Validation of clinical diagnostic criteria for Alzheimer’s disease. Ann. Neurol. 24: 17–22,1988.PubMedCrossRefGoogle Scholar
  44. 44.
    Morris J.C., McKeel D.W.Jr., Price J.L., LaBarge E., Vendegna T.R., Rubin E.H., Berg L., Ball M.J.: Very mild senile dementia of the Alzheimer’s type (SDAT). Neurology 38 (Suppl. 1): 227,1988. (Abstract).CrossRefGoogle Scholar
  45. 45.
    Pfeiffer E.: A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. J. Am. Geriatr. Soc. 23:433–441,1975.PubMedGoogle Scholar
  46. 46.
    Faber-Langendoen K., Morris J.C., Knesevich J.W., Berg L.: Aphasia in senile dementia of the Alzheimer’s type. Ann. Neurol. 23: 365–370, 1988.PubMedCrossRefGoogle Scholar
  47. 47.
    Zarit S.H., Miller N.E., Kahn R.L.: Brain function, intellectual impairment and education in the aged. J. Am. Geriatr. Soc. 26: 58–67, 1978.PubMedGoogle Scholar
  48. 48.
    Storandt M., Botwinick J., Danziger W.L., Berg L., Hughes C.P.: Psychometric differentiation of mild senile dementia of the Alzheimer’s type. Arch. Neurol. 41: 497–499, 1984.PubMedCrossRefGoogle Scholar
  49. 49.
    Kaplan E., Goodglass H., Weintraub S.: Boston Naming Test, Experimental Edition. Boston, MA, Veterans Administration Hospital, 1976.Google Scholar
  50. 50.
    Wechsler D.: Manual: Wechsler Adult Intelligence Scale. New York, Psychological Corporation, 1955.Google Scholar
  51. 51.
    Armitage S.G.: An analysis of certain psychological tests used for the evaluation of brain injury. Psychol. Med. (Monogr. Suppl.) 60: 1–48, 1946.Google Scholar
  52. 52.
    Morris J.C., Fulling K.: Early Alzheimer’s disease: diagnostic considerations. Arch. Neurol. 45: 345–349, 1988.PubMedCrossRefGoogle Scholar
  53. 53.
    Morris J., LaBarge E., Clark C., et al: CERAD clinical and neuropsychological assessment of Alzheimer’s disease: a preliminary report of standardized procedures and reliability. Neurology 38 (Suppl. 1): 287, 1988. (Abstract).Google Scholar
  54. 54.
    Mirra S.S., Vogel F.S., Hughes J.P., Brownlee L.M., Heyman A.: The CERAD protocol for the neuropatho- logic assessment of Alzheimer’s disease and related disorders. Neurology 38 (Suppl. 1): 413, 1988.CrossRefGoogle Scholar

Copyright information

© Editrice Kurtis s.r.l. 1990

Authors and Affiliations

  • John C. Morris
    • 1
  1. 1.The Memory and Aging ProjectWashington University School of MedicineSt. LouisUSA

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