Compliance bei Arzneimitteln: ein unterschätztes Problem

  • Michael M. Brucksch
  • Thomas Teyke
  • Christian Lenz
  • Marc O. Schurr

Compliance with medication: an underestimated problem


Non-Compliance with the prescribed medications has been a common concern in medical practice for a long time. Patients do not fully adhere to their prescriptions for medications or do not continue with their medications for as long as is recommended even when their conditions are potentially life threatening. As a consequence, this behavior may not only harm the individual patient by reducing the potential benefits of drug therapy, requiring additional treatment, but it does also lead to a wasting of resources. In this paper, we review studies that address the true dimensions of the problem, the factors involved, and the strategies used to improve compliance. Our findings document that in order to improve compliance, combined strategies such as a cooperative patient-doctor-relationship, promotion of patient self-management, or simplification of the drug regimen by combination therapy and therapy plans have the highest success rate. Further research on strategies to reduce non-compliance, the impact of non-compliance on health outcomes, and on health costs are needed.


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Copyright information

© Adis International Limited 2005

Authors and Affiliations

  • Michael M. Brucksch
    • 1
  • Thomas Teyke
    • 2
  • Christian Lenz
    • 3
  • Marc O. Schurr
    • 1
  1. 1.IHCI Institute of Healthcare IndustriesSteinbeis University BerlinBerlinDeutschland
  2. 2.BTP ResearchKölnDeutschland
  3. 3.Pfizer Pharma GmbHKarlsruheDeutschland

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