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5.6 The HYPERPRACT Study: a Multicentre Survey on the Accuracy of the Echocardiographic Assessment of Hypertensive Left Ventricular Hypertrophy In Clinical Practice

  • C. Cuspidi
  • M. Maisaidi
  • F. Negri
  • C. Cuspidi
  • C. Valerio
  • V. Giudici
  • C. Sala
  • M.L. Muiesan
  • A.M. Grandi
  • G. Palombo
  • C. Pini
  • A. Zanchetti
  • G. Mancia
Contributions from International Congress Heart
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5.6 The HYPERPRACT Study: a Multicentre Survey on the Accuracy of the Echocardiographic Assessment of Hypertensive Left Ventricular Hypertrophy In Clinical Practice

Introduction. Left ventricular hypertrophy (LVH) assessed by echocardiography has a relevant impact in clinical decision making in hypertensive patients.

Aim. We investigated the precision and accuracy of hypertensive LVH determination in current clinical practice by a regional-based survey.

Methods. The study included 211 patients with essential hypertension consecutively attending six hospital out-patient hypertension clinics in the northern Italian region of Lombardy; all subjects had undergone an echocardiographic examination for hypertension related problems in a non-academic or research ultrasound laboratory within two years. The original echocardiographic report was examined to ascertain whether the diagnosis of LVH was based on calculation of LV mass according to validated formulae and indexed to body size (primary outcome) and whether LV geometrical patterns and indices of diastolic function were provided (secondary outcome).

Results. A total of 211 echocardiograms performed by 120 physicians operating in 73 different hospital and out-of-hospital ultrasound laboratories were collected. Absolute LV mass, LV mass index and relative wall thickness were calculated in 45.5 %, 24.6 % and 12.3% of the cases, respectively. Parameters of LV diastolic filling were measured in two-thirds of the cases and estimation of E/A ratio was provided by less than 20% of the examinations.

Conclusions. This study shows that a large majority of echocardiographic examinations routinely performed in hypertensive subjects in order to detect cardiac damage, do not report qualifying data on LV mass, LV geometry and diastolic function. These results indicate that a quantitative assessment of LVH and LV function is rarely provided in clinical practice.

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Authors and Affiliations

  • C. Cuspidi
    • 1
  • M. Maisaidi
    • 3
  • F. Negri
    • 1
    • 2
  • C. Cuspidi
    • 1
    • 2
  • C. Valerio
    • 2
  • V. Giudici
    • 2
  • C. Sala
    • 3
  • M.L. Muiesan
    • 4
  • A.M. Grandi
    • 1
  • G. Palombo
    • 1
  • C. Pini
    • 1
  • A. Zanchetti
    • 2
    • 4
  • G. Mancia
    • 1
    • 2
  1. 1.Istituto Auxologico ItalianoMilanoItaly
  2. 2.Dipartimento di Medicina Clinica e PrevenzioneUniversità di Milano - BicoccaMilanItaly
  3. 3.Istituto di Medicina CardiovascolareOspedale Maggiore Policlinico Mangiagalli and IRCCS Regina ElenaMilanoItaly
  4. 4.Centro Interuniversitario di Fisiologia Clinica e IpertensioneUniversità di MilanoItaly

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