The Battle Against Hormone-Refractory Prostate Cancer
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Approximately 234 000 American men will be diagnosed with prostate cancer in 2006 and many will require treatment. One of the major medical needs for this patient group is a therapeutic option for hormone-refractory prostate cancer (HRPC) when standard care with Taxotere® (docetaxel) is ineffective.
The main hope for second-line therapy of HRPC is satraplatin, a novel oral platinum drug in development with the German company GPC Biotech. Satraplatin is currently being investigated for second-line therapy of HRPC in a pivotal phase III trial, and GPC Biotech began filing for US FDA approval of the drug in December 2005 by way of a rolling New Drug Application. An independent data monitoring board recommended in April that the trial should continue through to completion. Efficacy data are anticipated to become available in Q3 of 2006 and, assuming positive results, the FDA filing may be completed by year-end — suggesting that satraplatin could be on the market within a...
KeywordsProstate Cancer Docetaxel Estramustine Taxotere Pivotal Phase
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