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Molecular Diagnosis & Therapy

, Volume 13, Issue 6, pp 407–412 | Cite as

From the Literature

Case Reports
News
  • 14 Downloads

Contents

  • 1. Antineoplastics

  • 2. Antivirals

  • 3. Cardiovascular Therapies

  • 4. Endocrine Disorder Therapies

  • 5. Immunosuppressants

  • 6. Neurologic and Psychiatric Therapies

  • 7. Osteoporosis Therapies

  • 8. Skin Disorder Therapies

1. Antineoplastics

Cyclophosphamide/Melphalan: Early-Onset Acute Lymphoblastic Leukemia in a Patient with Multiple Myeloma: Case Report

A 61-year-old woman with multiple myeloma developed acute lymphoblastic leukemia (ALL) with mixed-lineage leukemia gene (MLL) rearrangement after receiving cyclophosphamide and melphalan [durations of therapies not stated].

The woman presented in January 2007. She was diagnosed with multiple myeloma; she had a normal karyotype (46,XX[20/20]). In July 2007, following 4 cycles of high-dose dexamethasone, her peripheral blood stem cells were mobilized and collected using cyclophosphamide 4 g/m2 and granulocyte colony-stimulating factor. In August 2007, she underwent autologous stem-cell transplantation with high-dose melphalan (200 mg/m2) as...

Reference

  1. Ueda K, Yamamoto G, Shinohara A, et al. Early onset of acute lymphoblastic leukemia with MLL rearrangement after autologous stem cell transplantation for multiple myeloma. Ann Hematol 2009; 88 (8): 813–4Google Scholar

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  1. Perianez-Parraga L, Perez-Rodriguez O, Do Pazo-Oubina F, et al. Acute toxicity of high doses of methotrexate in treatment of ALL in children: a case study. Farm Hosp 2009; 33(3): 172–3PubMedCrossRefGoogle Scholar

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  1. Burroughs JR. Management of intractable postoperative blepharoplasty bleeding after thrombolysis for a pulmonary embolism. Ophthal Plast Reconstr Surg 2009; 25(4): 314–5PubMedCrossRefGoogle Scholar

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  1. Kato T, Miura M, Kishikawa H, et al. Rhabdomyolysis in kidney transplantation induced by extremely high level of serum cyclosporine due to the disorder in metabolic enzyme and transporters [abstract no. P-255]. 14th Congress, European Society for Organ Transplantation; 2009 Aug 30–Sep 2; ParisGoogle Scholar

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  1. Ammatuna E, Montefusco E, Pacilli M, et al. Use of arsenic trioxide in secondary acute promyelocytic leukemia developing after treatment of multiple sclerosis with mitoxantrone. Leuk Lymphoma 2009; 50(7): 1217–8PubMedCrossRefGoogle Scholar

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  1. Bolszak M, Anttonen AK, Komulainen T, et al. Digenic mutations in severe myoclonic epilepsy of infancy. Epilepsy Res 2009; 85(2-3): 300–4PubMedCrossRefGoogle Scholar

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  1. McNeil JJ, Ronaldson KJ, Taylor AJ, et al. Diagnostic features of clozapine-induced myocarditis [abstract no. P5585]. 2009 Congress, European Society of Cardiology; 2009 Aug 29–Sep 2; BarcelonaGoogle Scholar

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  1. Vairaktaris E, Vassiliou S, Avgoustidis D, et al. Bisphosphonate-induced avascular osteonecrosis of the mandible associated with a common thrombophilic mutation in the prothrombin gene. J Oral Maxillofac Surg 2009; 67(9): 2009–12PubMedCrossRefGoogle Scholar

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