Huge localized mesothelioma of the diaphragm in a 17-year-old Female — a case report with calculated tumor volume doubling time —

  • Kenji Kawashima
  • Kohei Yokoi
  • Haruhisa Matsuguma
  • Noriki Kamiya
  • Naoto Miyazawa
Case Report


An operative case of localized mesothelioma of the pleura developed in a 17-year-old female was reported. She was admitted to our hospital complaining of right chest pain. A chest X-ray film showed a huge mass in the right lower field of the lung. After the embolization of the right inferior phrenic artery, which was the main feeder to the tumor, it was then successfully resected combined with the right diaphragm and the right lower lobe of the lung. Histologicaly, the tumor was diagnosed as benign localized mesothelioma (solitary fibrous tumor of the pleura). Further histological and immunohistochemical study revealed that it had developed from the connective tissue under the parietal mesothelium of the diaphragm. As chest roentgenograms had been undertaken during past two years, the tumor volume doubling time was calculated at 153 days. Despite the short tumor volume doubling time as like primary lung cancer, she is alive without recurrence 5 years after the operation.


Solitary Fibrous Tumor Primary Lung Cancer Chest Roentgenogram Inferior Phrenic Artery Tumor Volume Doubling Time 
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Copyright information

© Springer Fachmedien Wiesbaden GmbH 1998

Authors and Affiliations

  • Kenji Kawashima
    • 1
  • Kohei Yokoi
    • 1
  • Haruhisa Matsuguma
    • 1
  • Noriki Kamiya
    • 1
  • Naoto Miyazawa
    • 1
  1. 1.Division of Thoracic SurgeryTochigi Cancer CenterUtsunomiyaJapan

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