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Journal of the Iranian Chemical Society

, Volume 6, Issue 3, pp 588–593 | Cite as

A highly efficient michael addition of indoles to α,β-unsaturated electron-deficient compounds in acidic SDS micellar media

  • A. A. Jafari
  • F. Moradgholi
  • F. Tamaddon
Article

Abstract

The Michael addition of indoles to α,β-unsaturated electron deficient compounds was catalyzed efficiently at room temperature in acidic micellar solution of sodium dodecyl sulfate (SDS). The substitution on the indole nucleus occurred exclusively at the 3-position in good to excellent yields, and no N-alkylation products were observed.

Keywords

Michael addition Indole α,β-Unsaturated electron-deficient compounds Micellar media 

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Copyright information

© Iranian Chemical Society 2009

Authors and Affiliations

  1. 1.Department of Chemistry, Faculty of ScienceYazd UniversityYazdIran

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