Sparse data analysis

  • L. Aarons


In recent years there has been a growing interest in techniques capable of analyzing sparse data, particularly gathered during Phase III clinical trials, and there is now pressure on manufacturers to obtain more kinetic and dynamic information from Phase III studies. Techniques for the analysis of sparse data are reviewed drawing on a number of examples taken from pharmacokinetic and pharmacodynamic experiments.


Sparse data analysis population pharmacokinetics pharmacodynamics NONMEM drug development 


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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • L. Aarons
    • 1
  1. 1.Pharmacy DepartmentUniversity of ManchesterManchesterUK

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