Advertisement

Combined partial sternectomy for thymic carcinoma

  • Kenro Takahashi
  • Junji Yoshida
  • Mitsuyo Nishimura
  • Kanji Nagai
Case Report

Abstract

For thymic carcinoma, a 67-year-old Japanese female underwent combined chemotherapy, to which a partial response was registered. Afterwards, total thymectomy with combined en bloc resection of the biopsy site, the partial sternum and the partial mediastinal components were completed with a clear margin. Skeletal reconstruction was performed using polypropylene mesh. Paradoxical movement of the chest wall was tolerable. Functional and cosmetic appearance of the chest wall following the reconstruction was satisfactory. Thirty-nine months had passed since the onset of the chemotherapy, when local recurrence was detected in the approximated major pectoral muscle. The patient underwent salvage radiation therapy that resulted in a complete response, and is currently alive and disease free at 46 months after the onset of the combined chemotherapy.

Key words

thymic carcinoma squamous cell carcinoma preoperative chemotherapy partial sternectomy salvage radiation therapy 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Deschamps C, Tirnaksiz BM, Darbandi R, Trastek VF, Allen MS, Miller DL, et al. Early and long-term results of prosthetic chest wall reconstruction. J Thorac Cardiovasc Surg 1999; 117: 588–92.PubMedCrossRefGoogle Scholar
  2. 2.
    Hsu CP, Chen CY, Chen CL, Lin CT, Hsu NY, Wang JH, et al. Thymic carcinoma: ten years’ experience in twenty patients. J Thorac Cardiovasc Surg 1994; 107: 615–20.PubMedGoogle Scholar
  3. 3.
    Macchiarini P, Chella A, Ducci F, Rossi B, Testi C, Bevilacqua G, et al. Neoadjuvant chemotherapy, surgery, and postoperative radiation therapy for invasive thymoma. Cancer 1991; 68: 706–13.PubMedCrossRefGoogle Scholar
  4. 4.
    Martini N, Huvos AG, Burt ME, Heelan RT, Bains MS, McCormack PM, et al. Predictors of survival in malignant tumors of the sternum. J Thorac Cardiovasc Surg 1996; 111: 96–106.PubMedCrossRefGoogle Scholar
  5. 5.
    Pairolero PC, Arnold PG. Chest wall tumors: experience with 100 consecutive patients. J Thorac Cardiovasc Surg 1985; 90: 367–72.PubMedGoogle Scholar
  6. 6.
    Soysal O, Walsh GL, Nesbitt JC, McMurtrey MJ, Roth JA, Putnum JB Jr. Resection of sternal tumors: extent, reconstruction, and survival. Ann Thorac Surg 1995; 60: 1353–9.PubMedCrossRefGoogle Scholar
  7. 7.
    Weide LG, Ulbright TM, Loehrer PJ, Williams SD. Thymic carcinoma: a distinct clinical entity responsive to chemotherapy. Cancer 1993; 71: 1219–23.PubMedCrossRefGoogle Scholar

Copyright information

© The Japanese Society of Thoracic and Cadiovascular Surgery 2000

Authors and Affiliations

  • Kenro Takahashi
    • 1
  • Junji Yoshida
    • 1
  • Mitsuyo Nishimura
    • 1
  • Kanji Nagai
    • 1
  1. 1.Division of Thoracic SurgeryGunma Cancer Center HospitalOtaJapan

Personalised recommendations