European Journal of Clinical Pharmacology

, Volume 40, Supplement 1, pp S19–S21 | Cite as

Inhibition of cholesterol absorption by HMG-CoA reductase inhibitor

  • T. A. Miettinen


In subjects with familial hypercholesterolemia cholesterol absorption efficiency was insignificantly reduced during a short-term more consistently during long-term pravastatin treatment. A cholesterol feeding had no effect on LDL cholesterol level but reduced absorption efficiency during a long-term lovastatin treatment.

Key words

Statins lathosterol methyl sterols cholesterol absorption LDL cholesterol dietary cholesterol 


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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • T. A. Miettinen
    • 1
  1. 1.Second Department of MedicineUniversity of HelsinkiHelsinkiFinland

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