, Volume 21, Issue 1, pp 73–74 | Cite as

‘Obligatory’ association between A and D cells demonstrated by bipolar islets in neonatal pancreas

Letters to the Editor


Glucagon Pancreatic Polypeptide Dysostosis Hyperinsulinemic Hypoglycemia Large Islet 


  1. 1.
    Orci L, Perrelet A (1979) La microarchitecture des îlots de Langerhans. Pour la Science 22: 30–44Google Scholar
  2. 2.
    Orci L (1977) A multihormonal micro-organ. In: Bajaj JS (ed) Insulin and Metabolism. Excerpta Medica, Amsterdam, pp 1–11Google Scholar
  3. 3.
    Orci L, Unger R (1975) Functional subdivision of islets of Langerhans and possible role of D cells. Lancet II: 1243–1244CrossRefGoogle Scholar
  4. 4.
    Unger RH, Dobbs RE, Orci L (1978) Insulin, glucagon and somatostatin secretion in the regulation of metabolism. Ann Rev Physiol 40: 307–343CrossRefGoogle Scholar
  5. 5.
    Orci L, Malaisse-Lagae F, Baetens D, Perrelet A (1978) Pancreatic polypeptide-rich regions in human pancreas. Lancet II: 1200–1201CrossRefGoogle Scholar
  6. 6.
    Coons AH, Leduc EH, Connolly JM (1955) Studies on antibody production. I. A method for the histochemical demonstration of specific antibody and its application to a study of the hyperimmune rabbit. J Exp Med 102: 49–63PubMedCrossRefGoogle Scholar
  7. 7.
    Robb P (1961) The development of the islet of Langerhans in the human foetus. J Exp Physiol 46: 335Google Scholar
  8. 8.
    Falin LI (1967) The development and cytodifterentiation of the islets of Langerhans in human embryos and foetuses. Acta Anat (Basel) 68: 147–168CrossRefGoogle Scholar
  9. 9.
    Jaffe R, Hashida Y, Yunis EJ (1980) Pancreatic pathology in hyperinsulinemic hypoglycemia of infancy. Lab Invest 42: 356–365PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • L. Orci
    • 1
  1. 1.Institute of Histology and EmbryologyUniversity of Geneva Medical SchoolGeneva 4Switzerland

Personalised recommendations