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Mycotoxin Research

, Volume 1, Issue 2, pp 65–69 | Cite as

Effect of different antioxidants and free radical scavengers on aflatoxin production

  • C. Fanelli
  • A. A. Fabbri
  • S. Pieretti
  • E. Finotti
  • S. Passi
Article

Abstract

Different antioxidants and free radical scavengers on aflatoxin production are analysed. The different compounds at different concentration were used: buthylated hydroxyanisole (BHA), buthylated hydroxytoluene (BHT), α-tocopherol (vitamin E), ascorbic acid (vitamin C), reduced glutathione, cysteine, cysteamine. The above compounds were tested in culture ofAspergillus parasiticus supplemented with carbon tetrachloride, a potent stimulating agent of aflatoxin biosynthesis.

Cysteamine and BHA highly inhibited the aflatoxin production induced by carbon tetrachloride, the inhibition decreased by lowering the concentration.

On the contrary, vitamin E, vitamin C, reduced glutathione and cysteine further enhanced the carbon tetrachloride stimulating effect. The addition of the above compounds did not significantly affect the growth of the fungal mycelia.

Keywords

Aflatoxin Free Radical Scavenger Carbon Tetrachloride Reduce Glutathione Cysteamine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Society of Mycotoxin Research and Springer 1985

Authors and Affiliations

  • C. Fanelli
    • 1
  • A. A. Fabbri
    • 1
  • S. Pieretti
    • 1
  • E. Finotti
    • 2
  • S. Passi
    • 2
  1. 1.Dipartimento di Biologia vegetaieUniversità di Roma «La Sapienza» Largo Cristina di SveziaRomaItaly
  2. 2.Istituto San Gallicano (IFO)RomaItaly

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