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Patulin degradation in saccharomyces cerevisiae: Sensitive mutants

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Conclusion

The present experiments (sensitive mutants and transient inhibition of growth) are compatible with the synthesis of an inductible detoxifying substance in the wild type strain. This substance could be glutathione because glutathione detoxification scheme essentially involves properties of the SH group and it is well known that patulin reacts with sulfhy dril groups.

Studies are presently being carried out with sensitive mutants to establish definitively the relation between intracellular pool of glutathone and the resistance mechanism of a yeast to patulin.

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References

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Authors and Affiliations

  1. Faculté des Sciences Agronomiques de l’Etat, 5800, Gembloux, Belgique

    Ph. Thonart & Z. L. Sumbu

  2. Institut de Recherches et Institut des Industries de Fermentation CERIA, 1070, Bruxelles, Belgique

    J. Bechet

Authors
  1. Ph. Thonart
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  2. Z. L. Sumbu
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  3. J. Bechet
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Thonart, P., Sumbu, Z.L. & Bechet, J. Patulin degradation in saccharomyces cerevisiae: Sensitive mutants. Mycotox Res 1, 37–40 (1985). https://doi.org/10.1007/BF03191953

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  • DOI: https://doi.org/10.1007/BF03191953

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