Abstract
In order to produce deoxynivalenol (DON), conditions for the production of 3-acetyldeoxynivalenol (Ac-DON) in shake culture were studied. A selected isolate of DON-producer,F. graminearum strain R2118, produced about 70mg/mL of Ac-DON when cultured at 25°C for 4 days in a medium consisting of 3% sucrose, 0.1% peptone, and 0.1% yeast extract. From the mass culture (10 L) of the strain, 792 mg of Ac-DON were isolated and 384 mg of DON were obtained after hydrolysis of the acetate.
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Ishii, K., Sato, H. & Ueno, Y. Production of 3-acetyldeoxynivalenol in shake culture. Mycotox Res 1, 19–24 (1985). https://doi.org/10.1007/BF03191950
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DOI: https://doi.org/10.1007/BF03191950