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Mycotoxin Research

, Volume 1, Issue 1, pp 19–24 | Cite as

Production of 3-acetyldeoxynivalenol in shake culture

  • K. Ishii
  • H. Sato
  • Y. Ueno
Article

Abstract

In order to produce deoxynivalenol (DON), conditions for the production of 3-acetyldeoxynivalenol (Ac-DON) in shake culture were studied. A selected isolate of DON-producer,F. graminearum strain R2118, produced about 70mg/mL of Ac-DON when cultured at 25°C for 4 days in a medium consisting of 3% sucrose, 0.1% peptone, and 0.1% yeast extract. From the mass culture (10 L) of the strain, 792 mg of Ac-DON were isolated and 384 mg of DON were obtained after hydrolysis of the acetate.

Keywords

Graminearum Sucrose Concentration Trichothecene Fusarium Species Zearalenone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Society of Mycotoxin Research and Springer 1985

Authors and Affiliations

  • K. Ishii
    • 1
  • H. Sato
    • 1
  • Y. Ueno
    • 1
  1. 1.Department of Toxicology and Microbial Chemistry, Faculty of Pharmaceutical SciencesScience University of TokyoTokyoJapan

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