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The metabolism of saddamine in man: The fate of the benzylamine moiety of saddamine

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Summary

The metabolism of14C-saddamine radiolabelled in the benzylamine moiety has been investigated in man after oral administration.14C-Hippuric acid was found to be the only radiolabelled urinary metabolite, the overall amount of which was equivalent to over 95% of the dose. The time taken for elimination of 50% of the dose in the urine was approximately five hours and the corresponding value for14C-benzylamine hydrochloride was less than one hour. Department of Biochemistry, College of

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  1. M. R. Al-Ani

    Present address: Department of Biochemistry, College of Medicine, University of Baghdad, Iraq

Authors and Affiliations

  1. Department of Biochemistry, Charing Cross Hospital Medical School, Hammersmith, W6 8RF, London, England

    M. R. Al-Ani, S. G. Wood & A. Lawson

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  1. M. R. Al-Ani
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  2. S. G. Wood
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  3. A. Lawson
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Al-Ani, M.R., Wood, S.G. & Lawson, A. The metabolism of saddamine in man: The fate of the benzylamine moiety of saddamine. European Journal of Drug Metabolism and Pharmacokinetics 4, 117–119 (1979). https://doi.org/10.1007/BF03189411

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  • DOI: https://doi.org/10.1007/BF03189411

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