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Endothelial dysfunction and microalbuminuria precede platelet function abnormalities in patients with insulin dependent diabetes

  • M. Joyce
  • K. Moore
  • G. McGreal
  • C. Thompson
  • C. J. Kelly
  • D. Cox
  • D. J. Bouchier-Hayes
Poster Session
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Conclusion

Using the above parameters, these data demonstrate that this population of type 1 diabetics have no evidence of platelet abnormalities. Further, they indicate that anti-platelet therapy is not required in the early stages of type 1 diabetes and that endothelial dysfunction precedes and is a potential mediator of diabetic platelet dysfunction.

Copyright information

© Springer 2002

Authors and Affiliations

  • M. Joyce
    • 1
    • 4
  • K. Moore
    • 2
    • 4
  • G. McGreal
    • 1
    • 4
  • C. Thompson
    • 2
    • 4
  • C. J. Kelly
    • 1
    • 4
  • D. Cox
    • 3
  • D. J. Bouchier-Hayes
    • 4
  1. 1.Department of SurgeryRCSI Education and Research CentreDublinIreland
  2. 2.Department of EndocrinologyRCSI Education and Research CentreDublinIreland
  3. 3.Department of PharmacologyDublinIreland
  4. 4.Royal College of SurgeonsRCSI Education and Research CentreDublinIreland

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