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Endothelial dysfunction and microalbuminuria precede platelet function abnormalities in patients with insulin dependent diabetes

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Conclusion

Using the above parameters, these data demonstrate that this population of type 1 diabetics have no evidence of platelet abnormalities. Further, they indicate that anti-platelet therapy is not required in the early stages of type 1 diabetes and that endothelial dysfunction precedes and is a potential mediator of diabetic platelet dysfunction.

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Authors and Affiliations

  1. Department of Surgery, RCSI Education and Research Centre, Dublin, Ireland

    M. Joyce, G. McGreal & C. J. Kelly

  2. Department of Endocrinology, RCSI Education and Research Centre, Dublin, Ireland

    K. Moore & C. Thompson

  3. Department of Pharmacology, Dublin, Ireland

    D. Cox

  4. Royal College of Surgeons, RCSI Education and Research Centre, Dublin, Ireland

    M. Joyce, K. Moore, G. McGreal, C. Thompson, C. J. Kelly & D. J. Bouchier-Hayes

Authors
  1. M. Joyce
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  2. K. Moore
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  3. G. McGreal
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  4. C. Thompson
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  5. C. J. Kelly
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  6. D. Cox
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  7. D. J. Bouchier-Hayes
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Joyce, M., Moore, K., McGreal, G. et al. Endothelial dysfunction and microalbuminuria precede platelet function abnormalities in patients with insulin dependent diabetes. Ir J Med Sci 171 (Suppl 1), 45 (2002). https://doi.org/10.1007/BF03170403

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  • DOI: https://doi.org/10.1007/BF03170403

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