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Hypoxia protects human renal proximal tubular epithelial cells from cyctotoxic immunosuppressant medications and reperfusion injury in a model of kidney preservation

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Conclusions

Exposure of HK-2 cells to reperfusion may predispose them to further injury and death by immunosuppressants.This implies that pre-conditioning at the time of retrieval may prevent subsequent injury and thus DGF.

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Authors and Affiliations

  1. Dept. of Surgery, Conway Institute of Biomolecular and Biomedical Sciences, UCD, Belfield, Dublin

    P. Daly, D. A. Healy, R. E. Power, N. G. Docherty, J. M. Fitzpatrick & R. W. G. Watson

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  1. P. Daly
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  2. D. A. Healy
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  3. R. E. Power
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  4. N. G. Docherty
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  5. J. M. Fitzpatrick
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  6. R. W. G. Watson
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Daly, P., Healy, D.A., Power, R.E. et al. Hypoxia protects human renal proximal tubular epithelial cells from cyctotoxic immunosuppressant medications and reperfusion injury in a model of kidney preservation. Ir J Med Sci 174 (Suppl 1), 27 (2005). https://doi.org/10.1007/BF03170144

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  • DOI: https://doi.org/10.1007/BF03170144

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