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Diabetic nephropathy is ameliorated with HMG-co-enzyme A reductase treatment

  • R. G. Casey
  • M. Joyce
  • G. Roche-Nagle
  • M. J. O’Sullivan
  • D. C. Winter
  • C. J. Kelly
  • D. J. Bouchier-Hayes
Session 9 Urology

Conclusions

Pravastatin attenuates changes in serum creatinine, renal haemodynamics (renal flux and glomerular filtration rate [GFR]) and architectural distortion. It had no systemic effects on weight loss or serum lipid levels suggesting that reno-protection occurs locally and independent of lipid lowering.

Copyright information

© Springer 2002

Authors and Affiliations

  • R. G. Casey
    • 1
    • 2
  • M. Joyce
    • 1
    • 2
  • G. Roche-Nagle
    • 1
    • 2
  • M. J. O’Sullivan
    • 1
    • 2
  • D. C. Winter
    • 1
    • 2
  • C. J. Kelly
    • 1
    • 2
  • D. J. Bouchier-Hayes
    • 1
    • 2
  1. 1.Department of SurgeryRoyal College of Surgeons in IrelandIreland
  2. 2.Education and Research CentreBeaumont HospitalDublinIreland

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