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Platelet and endothelial abnormalities that contribute to atherogenesis are early alterations in young male smokers

  • R. G. Casey
  • G. Roche-Nagle
  • M. Joyce
  • F. Fennessy
  • C. J. Kelly
  • D. Cox
  • D. J. Bouchier-Hayes
Session 2 Vascular
  • 15 Downloads

Conclusion

The above data demonstrate that the endothelial dysfunction (FMD) previously demonstrated correlates with endothelial injury (vWF) and platelet abnormalities. These are early and possibly synergistic alterations in young smokers that contribute to the development of atherogenesis.

Copyright information

© Springer 2002

Authors and Affiliations

  • R. G. Casey
    • 1
  • G. Roche-Nagle
    • 1
  • M. Joyce
    • 1
  • F. Fennessy
    • 1
  • C. J. Kelly
    • 1
  • D. Cox
    • 2
  • D. J. Bouchier-Hayes
    • 1
  1. 1.Department of SurgeryRoyal College of Surgeons in Ireland, Education and Research Centre, Beaumont HospitalDublinIreland
  2. 2.Department of PharmacologyRoyal College of Surgeons in Ireland, Education and Research Centre, Beaumont HospitalDublinIreland

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