Advertisement

Applied Magnetic Resonance

, Volume 24, Issue 1, pp 97–103 | Cite as

Separation of cross-relaxation and exchange in two-site spin systems with weak spin-spin couplings

  • V. V. Klochkov
  • R. A. Shaikhutdinov
  • B. I. Khairutdinov
  • E. N. Klimovitskii
  • M. Findeisen
  • S. Berger
Article

Abstract

A ratio relating the cross-relaxation rates, rate constants, and cross-peak and diagonal peak integrals is used for the analysis of exchanging two-site spin systems with weak scalar spin-spin couplings to extract the rate constants and cross-relaxation rates contributing to the same cross-peaks in two-dimensional nuclear Overhauser enhancement spectra (2-D NOESY). The method to separate contributions from cross-relaxation and chemical exchange into the cross-peaks in NOESY spectra was applied to investigate the intramolecular dynamics of trisulfide 4H, 8H-naphtho[1,8-ef]1,2,3-trithiocine in solutions.

Keywords

Nuclear Magnetic Resonance Nuclear Magnetic Resonance Spectrum Methylene Proton Chemical Exchange NOESY Spectrum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Klochkov V.V., Karatayeva F.Kh., Shaikhutdinov R.A., Khairutdinov B.I., Molins M.-A., Pons M.: Appl. Magn. Reson.22, 431–438 (2002)CrossRefGoogle Scholar
  2. 2.
    Wagner R., Berger S.: J. Magn. Reson. A123, 119–124 (1996)CrossRefGoogle Scholar
  3. 3.
    Klochkov V.V., Shaikhutdinov R.A., Khairutdinov B.I., Berger S., Findeisen M.: Zh. Obshch. Khim.71, 1339–1341 (2001)Google Scholar
  4. 4.
    States D.J., Haberkorn R.A., Ruben D.J.: J. Magn. Reson.48, 286–292 (1982)Google Scholar
  5. 5.
    Ernst R.R., Bodenhausen B., Wokaun A.: Principles of Nuclear Magnetic Resonance in One and Two Dimensions, p. 610. Oxford: Oxford University Press 1987.Google Scholar
  6. 6.
    Wagner R., Bodenhausen G., Muller N., Rance M., Sorensen O.W., Ernst R., Wuthrich K.: J. Am. Chem. Soc.107, 6440–6446 (1985)CrossRefGoogle Scholar
  7. 7.
    Van der Ven F.J.M.: Multidimensional NMR in Liquids: Basic Principles and Experimental Methods, p. 399. New York: Wiley 1995.Google Scholar
  8. 8.
    Guttenberger H.G., Bestmann H.J., Dickert F.L., Jorgensen F.S., Snyder J.P.: J. Am. Chem. Soc.103, 159–168 (1981)CrossRefGoogle Scholar
  9. 9.
    Sandstrom J.: Dynamic NMR Spectroscopy, p. 226. London: Academic Press 1982; Aganov A.V., Klochkov V.V., Samitov Yu.Yu.: Usp. Khim.54, 1585–1612 (1985)Google Scholar
  10. 10.
    Klochkov V.V., Shaikhutdinov R.A., Nazyrova A.Z.: Zh. Fiz. Khim.74, 1757–1760 (2000)Google Scholar
  11. 11.
    Atkins P.W.: Physical Chemistry, p. 995. Oxford: Oxford University Press 1990.Google Scholar

Copyright information

© Springer 2003

Authors and Affiliations

  • V. V. Klochkov
    • 1
  • R. A. Shaikhutdinov
    • 1
  • B. I. Khairutdinov
    • 1
  • E. N. Klimovitskii
    • 1
  • M. Findeisen
    • 2
  • S. Berger
    • 2
  1. 1.Department of ChemistryKazan State UniversityKazanRussian Federation
  2. 2.Department of Chemistry and MineralogyUniversity of LeipzigLeipzigGermany

Personalised recommendations