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Annals of Nuclear Medicine

, Volume 10, Issue 2, pp 271–274 | Cite as

Application of Tc-99m-tetrofosmin as a tumor imaging agent: Comparison with Tl-201

  • Ali S. Arbab
  • Kiyoshi Koizumi
  • Takao Arai
  • Keiji Toyama
  • Tsutomu Araki
Short Communication

Abstract

Tc-99m-tetrofosmin SPECT was performed on 6 occasions in 4 patients with hypopharyngeal carcinoma, lung carcinoma, esophageal carcinoma and maxillary plasmocytoma and compared with Tl-201 SPECT. All lesions accumulated both Tc-99m-tetrofosmin and Tl-201. Early uptake ratios of Tc-99m-tetrofosmin were about 2 but those of Tl-201 were much higher (more than 3). Washout rates of Tc-99m-tetrofosmin were higher than those of Tl-201. There was a good positive correlation between the early uptake ratio of Tc-99m-tetrofosmin and that of Tl-201. The delayed uptake ratio and washout rate showed poor correlation. In conclusion, early uptakes of both the agents were similar but their retention patterns were different. Tc-99m-tetrofosmin may be used for tumor imaging though more studies are required to evaluate diagnostic accuracy and the significance of delayed images.

Key words

tumor Tc-99m-tetrofosmin Tl-201 dual isotopes SPECT 

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Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • Ali S. Arbab
    • 1
  • Kiyoshi Koizumi
    • 1
  • Takao Arai
    • 1
  • Keiji Toyama
    • 1
  • Tsutomu Araki
    • 1
  1. 1.Department of RadiologyYamanashi Medical UniversityYamanashiJapan

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