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Annals of Nuclear Medicine

, Volume 10, Issue 4, pp 445–448 | Cite as

Absent myocardial I-123 BMIPP uptake in a family

  • Eui-Hyo Hwang
  • Akira Yamashita
  • Hitoshi Takemori
  • Junichi Taki
  • Kenichi Nakajima
  • Hisashi Bunko
  • Saburou Nakamura
  • Takayuki Ikeda
  • Norihisa Tonami
Case Report

Abstract

A 72-year-old woman with hypertension showed no sign of myocardial accumulation of123I-BMIPP, and201Tl and123I-MIBG scintigraphy demonstrated normal findings. Electrocardiography showed left axis deviation with inverted T waves in leads I, aVL, V2–6 and QT prolongation. Coronary arteriography, two dimensional echo cardiography and laboratory data showed no abnormality. Her 66-year-old sister with non-insulin-dependent diabetes mellitus also had no myocardial BMIPP uptake, but had normal201Tl finding. ECG and chest film findings were normal. Laboratory data indicated slightly high fasted blood glucose, triglyceride and total cholesterol. Four sons of a 72-year-old woman also underwent BMIPP scintigraphy. No BMIPP uptake was also observed in her 2nd son (49 years old) and his electrocardiogram showed QT prolongation. Since these rare findings indicating no myocardial BMIPP uptake were seen in a family, we suspected that a hereditary myocardial metabolic abnormality accounted for them.

Key words

I-123 BMIPP hereditary abnormality myocardial fatty acid metabolism 

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Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • Eui-Hyo Hwang
    • 1
  • Akira Yamashita
    • 2
  • Hitoshi Takemori
    • 2
  • Junichi Taki
    • 3
  • Kenichi Nakajima
    • 3
  • Hisashi Bunko
    • 4
  • Saburou Nakamura
    • 2
  • Takayuki Ikeda
    • 2
  • Norihisa Tonami
    • 3
  1. 1.Department of RadiologyTsuruga City HospitalFukuiJapan
  2. 2.Cardiovascular CenterTsuruga City HospitalJapan
  3. 3.Department of Nuclear MedicineKanazawa University, Faculty of MedicineJapan
  4. 4.Department of Medical InformaticsKanazawa University, Faculty of MedicineJapan

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