Advertisement

Annals of Nuclear Medicine

, Volume 12, Issue 3, pp 149–151 | Cite as

Scintigraphic diagnosis of intrathoracic extramedullary hematopoiesis in a patient with β-thalassemia

  • Aysun Özdemir
  • Firat Güngör
  • Fatma Tunçdemir
  • Metin Çubuk
  • Binnur Karayalçin
Case Report

Abstract

We report the scintigraphic diagnosis of intrathoracic extramedullary hematopoiesis (EMH) in a patient with β-thalassemia. A patient had a mass in the right thoracic paravertebral region on radiography and CT. Bone marrow imaging of the thorax by means of both Tc-99m nanocolloid and phytate demonstrated uptake of the tracer in the mediastinal mass, establishing the diagnosis of EMH.

Key words

extramedullary hematopoiesis bone marrow imaging β-thalassemia 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Bronn JL, Paquelet JR, Tetalman MR. Intrathoracic extramedullary hematopoiesis: appearance of Tc-99m sulfur colloid marrow scan.Am J Roentgenol 134: 1254–1255, 1980.Google Scholar
  2. 2.
    Adams BK, Jacobs P, Byrne MJ, Bird AR, Boniaczszuk J. Fe-52 imaging of intrathoracic extramedullary hematopoiesis in a patient with β thalassemia.Clin Nucl Med 20 (7): 619–622, 1995.PubMedCrossRefGoogle Scholar
  3. 3.
    Coates GG, Eisenberg B, Dail DH. Tc-99m sulfur colloid demonstration of diffuse pulmonary interstitial extramedullary hematopoiesis in a patient with myelofibrosis. A case report and review of the literature.Clin Nucl Med 19 (12): 1879–1884, 1994.CrossRefGoogle Scholar
  4. 4.
    Reske SN. Recent advances in bone marrow scanning.Eur J Nucl Med 18: 203–221, 1991.PubMedCrossRefGoogle Scholar
  5. 5.
    Geeter FD, Renterghem DV. Scintigraphic diagnosis of intrathoracic extramedullary hematopoiesis in alcohol-related macrocytosis.J Nucl Med 37: 473–475, 1996.PubMedGoogle Scholar
  6. 6.
    Fielding JR, Owens M, Naimark A. Intrathoracic extramedullary hematopoiesis secondary to B12 and folate deficiency: CT appearance.J Comput Assist Tomogr 15: 308–310, 1991.PubMedCrossRefGoogle Scholar
  7. 7.
    De Montpreville VT, Dulmet EM, Chapelier AR, Dartevelle PG, Verley JM. Extramedullary hematopoietic tumors of the posterior mediastinum related to the asymptomatic refractory anemia.Chest 104: 1623–1624, 1993.PubMedCrossRefGoogle Scholar
  8. 8.
    Savader SJ, Otero RR, Saveder BL. MR imaging of intrathoracic extramedullary hematopoiesis.J Comput Assist Tomogr 12: 878–880, 1988.PubMedCrossRefGoogle Scholar
  9. 9.
    Murray IPC, Ell PJ. Marrow scintigraphy.In Nuclear Medicine in Clinical Diagnosis and Treatment, Reske SN (ed.), New York, Churchill Livingstone, Vol. 2, pp. 705–711, 1994.Google Scholar
  10. 10.
    Borgies P, Ferrant A, Leners N, et al. Diagnosis of heterotopic bone marrow in the mediastinum using Fe-52 and positron emission tomography.Eur J Nucl Med 15: 761–763, 1989.PubMedCrossRefGoogle Scholar
  11. 11.
    Gottschalk A, Hoffer PB, Potchen EJ, Berger HJ. Bone marrow imaging.In Diagnostic Nuclear Medicine, Alavi A, Heyman S (eds.), Baltimore, Williams-Wilkins, Vol. 2, pp. 707–725, 1988.Google Scholar
  12. 12.
    Datz FL. Hematologic imaging.In Handbook of Nuclear Medicine, Datz FL (ed.), Missouri, Mosby-Year Book, pp. 232–262, 1993.Google Scholar

Copyright information

© Springer-Verlag 1998

Authors and Affiliations

  • Aysun Özdemir
    • 1
  • Firat Güngör
    • 1
  • Fatma Tunçdemir
    • 1
  • Metin Çubuk
    • 2
  • Binnur Karayalçin
    • 1
  1. 1.Department of Nuclear MedicineAkdeniz University Faculty of MedicineArapsuyu, AntalyaTurkey
  2. 2.Department of RadiologyAkdeniz University Faculty of MedicineTurkey

Personalised recommendations