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Molecular and Chemical Neuropathology

, Volume 13, Issue 3, pp 225–232 | Cite as

Urinary excretion of metabolites of norepinephrine in Tourette’s syndrome

  • Glen B. Baker
  • Robert A. Bornstein
  • Alan B. Douglass
  • Alan Carroll
  • Gordon King
Article

Abstract

Urinary excretion of the norepinephrine metabolites 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) and normetanephrine (NME) was measured in Tourette’s Syndrome (TS) patients and in control subjects matched for age and education. The 24-h excretion (expressed per gram of creatinine) of total MHPG and of free and total (free + conjugated) NME was significantly lower in TS patients than in the normal subjects.

Index Entries

3-methoxy-4-hydroxyphenylethylene glycol (MHPG) norepinephrine normetanephrine Tourette’s syndrome 

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Copyright information

© Humana Press 1991

Authors and Affiliations

  • Glen B. Baker
    • 1
  • Robert A. Bornstein
    • 2
  • Alan B. Douglass
    • 1
  • Alan Carroll
    • 1
  • Gordon King
    • 1
  1. 1.PMHAC Research Unit, Department of PsychiatryUniversity of AlbertaEdmontonCanada
  2. 2.Department of PsychiatryOhio State UniversityColumbus

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