Zusammenfassung
Zur Herstellung von hochpräzisen Transplantaten aus menschlicher Hornhaut eignet sich die Abtragung mittels Excimer Laser bei 193 nm Wellenlänge besonders gut. Darauf basiert das Excimer Laser Corneal-Shaping-System (ELCS-S), mit dem aus Spenderhornhäuten in vitro durch Laserablation eine breite Palette verschiedener Dickenprofile herstellbar ist. Durch Verwendung eines unlängst implementierten Abtragungsalgorithmus (OSLA, Optimized Scanning Laser Ablation) konnte die Qualität der bearbeiteten Oberfläche wesentlich verbessert werden, wie anhand von elektronenmikroskopischen Aufnahmen demonstriert wird. Dadurch rückt die Verwendbarkeit von refraktiven Transplantaten (Lentikeln), insbesonders zur Korrektur von Weitsichtigkeit, in greifbare Nähe.
Abstract
To produce highly accurate transplants of human donor corneal tissue, Excimer Laser Ablation using 193 nm wavelength (as employed by the ELCS-System) is a well suited method. By using a recently developed ablation algorithm (Optimized Scanning Laser Ablation, OSLA), the surface smoothness has improved considerably as shown by scanning EM. Excimer laser treated surfaces can now be produced with deviations in smoothness of less than 10 μm.
Schrifttum
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Nach einem Vortrag gehalten am 21. April 1999 beim 3. Seminar der ÖGMA: „Medizin-Technik-Messtechnik” in Wien.
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Homolka, P., Biowski, R., Simader, C. et al. Das Excimer Laser Corneal Shaping-(ELCS-)System: hochpräzise Herstellung von Hornhaut- (Cornea-)Transplantaten mittels Excimer Laser-Ablation. Elektrotech. Inftech. 117, 265–268 (2000). https://doi.org/10.1007/BF03158628
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DOI: https://doi.org/10.1007/BF03158628
Schlüsselwörter
- Excimer Laser Corneal Shaping
- Optimized Scanning Laser Ablation
- penetrierende Keratoplastik
- lamellierende Epikeratoplastik
- Epikeratophakie