Skip to main content
SpringerLink
Log in

Are lymphocytes excitable cells?

  • Interdisciplinary
  • Published:
Acta Physica Hungarica

Abstract

Nerve and muscle cells are defined traditionally as excitable cells, due to their capacity to react to external stimuli with subsequent electric and/or mechanical responses.

Another category of cells, eminently among them the round-shaped blood cells, in particular the best studied lymphocytes, are classified as non-excitable cells.

We try to present evidence that lymphocytes may also be accepted as excitable cells. A bit far-reaching, further generalization could be formulated claiming that every cell can be considered as an excitable one.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. J. Szöllősi, S. Damjanocich, S.A. Mulhern and L. Trón, Progr. Biophys. molec. Biol.,49, 65, 1987.

    Article  Google Scholar 

  2. P. Cuatrecasas, The Harvey Lectures, Series,80, 89, 1986.

    Google Scholar 

  3. B. Alberts, D. Bray, J. Lewis, M. Raff, K. Roberts and D.D. Watson, Molecular Biology of the Cell, Garland Inc., New York and London, 1983.

    Google Scholar 

  4. M. Balázs, J. Matkó, J. Szöllősi, L. Mátyus, M.J. Fulwyler and S. Damjanovich, Biochem. Biophys. Res. Commun.,140, 999, 1986.

    Article  Google Scholar 

  5. P. Cuatrecasas, Ann. Rev. Biochem.,43, 169, 1974.

    Article  Google Scholar 

  6. D.R. Sibley, J.L. Benovic, M.G. Caron and R.J. Lefkowitz, Cell,48, 913, 1987.

    Article  Google Scholar 

  7. I.H. Pastan and M.C. Willingham, Ann. Rev. Physiol.,43, 239, 1981.

    Article  Google Scholar 

  8. M.J. Berridge and R.F. Irvine, Nature,312, 315, 1984.

    Article  ADS  Google Scholar 

  9. J. Cambier, J.G. Monroe, K.M. Coggeshall and J. Ranson, Immunology Today,6, 218, 1985.

    Article  Google Scholar 

  10. M.C. Sakar and L.E. Hokin, J. Membr. Biol.,89, 193, 1986.

    Article  Google Scholar 

  11. J.G. Monroe and M.C. Cambier, J. Exp. Med.,157, 2073, 1983.

    Article  Google Scholar 

  12. G.L. L’Allemain, A. Granchi, E. Cragoe, Jr. and J. Pouyssegur, J. Biol. Chem.,259, 4313, 1984.

    Google Scholar 

  13. R. Zidovetzki, Y. Yarden, J. Schlessinger and T.M. Jovin, Proc. Natl. Acad. Sci.,78, 6981, 1981.

    Article  ADS  Google Scholar 

  14. T.Y. Tsien, T. Pozzan and T.J. Rink, Nature,295, 68, 1982.

    Article  ADS  Google Scholar 

  15. M.J. Berridge and R.F. Irvine, Nature,312, 315, 1984.

    Article  ADS  Google Scholar 

  16. U. Nishizuka, Nature,308, 693, 1984.

    Article  ADS  Google Scholar 

  17. T.R. Hesketh, J.P. Moore, J.D.H. Morris, M.V. Taylor, J. Rogers, G.A. Smith and J.C. Metcalfe, Nature (Lond.),313, 481, 1985.

    Article  ADS  Google Scholar 

  18. P. Downes and R.H. Michell, Mol. Aspects Cell. Regul.,4, 2, 1985.

    Google Scholar 

  19. M.D. Housley, Trends Biochem. Sci.,12, 1, 1987.

    Article  Google Scholar 

  20. W. Siffert and J.W.N. Akkerman, Nature,325, 456, 1987.

    Article  ADS  Google Scholar 

  21. J.C. Cambier, J.G. Monroe, K.M. Coggeshall and J.T. Ransom, Immunol. Today,6, 218, 1985.

    Article  Google Scholar 

  22. L. Trón, J. Szöllősi, S. Damjanovich, S.H. Helliwell, D.J. Arndt-Jovin and T.M. Jovin, Biophys. J.,45, 939, 1984.

    Article  Google Scholar 

  23. J. Szöllősi, L. Trón, S. Damjanovich, S.H. Helliwell, D.J. Arndt-Jovin and T.M. Jovin, Cytometry,5, 210, 1984.

    Article  Google Scholar 

  24. S. Damjanovich, L. Trón, J. Szöllősi, R. Zidovetzki, W.L.C. Vaz, F. Regateiro, D.J. Arndt-Jovin and T.M. Jovin, Proc. Natl. Acad. Sci. USA,80, 5985, 1983.

    Article  ADS  Google Scholar 

  25. J. Szöllősi, L. Mátyus, M. Balász, I. Ember, M.J. Fulwyler and S. Damjanovich, Cytometry,8, 120, 1987.

    Article  Google Scholar 

  26. J. Szöllősi, S. Damjanovich, C.K. Goldman, M.J. Fulwyler, A. Aszalós, G. Goldstein, P. Rao, M.A. Talle, and T.A. Waldmann, Proc. Natl. Acad. Sci. USA,84, 7246, 1987.

    Article  ADS  Google Scholar 

  27. L. Trón, J. Szöllősi and S. Damjanovich, Immunol. Letter,16, 1, 1987.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biophysics, University Medical School of Debrecen, 4012, Debrecen, Hungary

    S. Damjanovich, Margit Balázs & J. Szöllősi

Authors
  1. S. Damjanovich
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Margit Balázs
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Szöllősi
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Dedicated to Academician D. Berényi on his 60th birthday

Rights and permissions

Reprints and permissions

About this article

Cite this article

Damjanovich, S., Balázs, M. & Szöllősi, J. Are lymphocytes excitable cells?. Acta Physica Hungarica 65, 349–353 (1989). https://doi.org/10.1007/BF03156082

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03156082

Keywords

Search

Navigation