Landau phenomenological theory of the pressure-induced phase transition of phospholipid bilayers

  • I. P. Sugár
  • I. Tarján


A theoretical model is developed to describe the temperature and pressure-induced phase transitions of phospholipid bilayer membranes simultaneously. By means of this model the phase transition enthalpies,-temperatures,-pressures and volume changes of different phospholipid membranes are calculated and compared with the available experimental data. Thep−T diagrams of the membranes are obtained, too. Phase diagrams for binary mixtures with components differing in chain length by 2 and 4 carbons are determined at different pressures. It is found that diagrams shift without significant deformation in their shape towards higher temperatures with increasing pressure.


Gibbs Free Energy Specific Volume DPPC Liquid Crystalline Phase Phase Transition Pressure 
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Copyright information

© with the authors 1981

Authors and Affiliations

  • I. P. Sugár
    • 1
  • I. Tarján
    • 1
  1. 1.Institute of BiophysicsSemmelweis Medical UniversityBudapestHungary

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