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Tijdschrift voor kindergeneeskunde

, Volume 68, Issue 2, pp 169–173 | Cite as

Risicofactoren voor het ontwikkelen van allergie op de kinderleeftijd vanuit epidemiologische optiek en strategieën voor de preventie van allergie

  • M. O. Hoekstra
  • J. G. Rijntjes
  • W. M. C. van Aalderen
Artikelen

Samenvatting

Verschillende factoren worden verondersteld een rol te spelen bij het ontstaan van allergie. Een onderverdeling is te maken in genetische factoren en pre- en postnatale omgevingsfactoren. Voorbeelden van prenatale omgevingsfactoren zijn roken door de moeder en dieet. Voorbeelden van postnatale risicofactoren zijn geboortemaand, infecties, darmflora, gezinsgrootte, inhalatieallergenen, (passief) roken en luchtvervuiling. Interventieonderzoek moet in de komende jaren laten zien hoe groot de invloed is van deze factoren. Strategieën voor de preventie van allergie moeten gericht zijn op alle factoren die betrokken zijn bij het ontstaan van allergie.

Summary

In the process of the development of allergy several prenatal and postnatal causating factors can be recognised. These factors are hereditary and pre- and postnatal environmental factors. Prenatal enviromental factors are maternal smoking and diet. Postnatal environmental factors are infections, the presence or absence of certain microorganisms in the gut flora, the number of siblings, allergy for inhaled allergens, air pollution and (passive) smoking. The exact impact of these factors on the development of allergy has yet to be determined by the outcome of several ongoing studies. Strategies for the prevention of allergic diseases will be directed towards all the contributing factors.

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Copyright information

© Bohn Stafleu van Loghum 2000

Authors and Affiliations

  • M. O. Hoekstra
    • 1
  • J. G. Rijntjes
  • W. M. C. van Aalderen
  1. 1.

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