Search for physiologically active compounds

Part 1. Synthesis of 7-amino and 7-halo-4-methyl-3-phenyl coumarins
  • N. V. Subba Rao
  • V. Sundaramurthy


7-Amino-4-methyl-3-phenyl coumarin has been prepared from 4-acetamido-o-hydroxy acetophenone. The corresponding halogen substituted coumarins, which are prepared through diazotisation and Sandmeyer reactions, have been found to be highly toxic to fish.


Coumarin Acetophenone Umbelliferones Phenyl Acetate Hydrobromic Acid 
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Copyright information

© Indian Academy of Sciences 1955

Authors and Affiliations

  • N. V. Subba Rao
    • 1
  • V. Sundaramurthy
    • 1
  1. 1.Chemistry DepartmentOsmania UniversityIndia

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