Search for physiologically active compounds

Part XXIV. Synthesis of 7, 8-furano, pyrono and 3-methyl-4-phenylcoumarins
  • M. Subramanyam Raju
  • N. V. Subba Rao


7-Hydroxy-3-methyl 4-phenylcoumarin andα-methyl dihydrofurano,α andγ-pyrono ring systems have been built on 7, 8-position of 4-phenylcoumarin. The bacteriostatic activity of these compounds as well as that of mammeisin and mesuol isolated fromMesua ferrea seeds has been evaluated. Structure-activity relationship among these compounds is discussed.


Coumarin Dilute Hydrochloric Acid Hexamine Allyl Bromide Hydrobromic Acid 
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Copyright information

© Indian Academy of Sciences 1974

Authors and Affiliations

  • M. Subramanyam Raju
    • 1
  • N. V. Subba Rao
    • 1
  1. 1.Department of ChemistryOsmania University, HyderabadA.P.

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