The action of calcium on blood vessels and its relation to hypertension

  • Sunita Inderjit Singh
  • Inderjit Singh


1. The action of calcium on the contractile mechanism of the unstriated muscle of the arterioles has been studied by prolonged immersion of dog’s hind limbs in solutions of calcium chloride and recording the rate of flow before and after immersion for 24 hours.

2. Isotonic solutions of calcium chloride produce a strong irreversible contraction of the arterioles. This is due to the action of calcium on the contractile mechanism.

3. The possible role of calcium in hypertension has been discussed.


Calcium Chloride Opposite Action Isotonic Solution Contractile Effect Unstriated Muscle 
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  1. Cappell, D. F...Muir’s Text Book of Pathology, 6th Edition, 1951, p. 301. Edward Arnold Press, London.Google Scholar
  2. Heilbrunn, L. V...An Outline of General Physiology, 3rd Edition, 1952, p. 423. W.B. Saunders Co., London.Google Scholar
  3. Singh, I...Proc. Ind. Acad. Sci., 1949,29, 190.Google Scholar
  4. Singh, I. and Singh, S. I... Ibid., 1949a,30, 270.Google Scholar
  5. —————.. Ibid., 1949b,30, 343.Google Scholar
  6. —————.. Ibid., 1950,32, 12.Google Scholar
  7. ----- ..Ibid., 1955.Google Scholar
  8. —————..Curr. Sci., 1948,17, 321.Google Scholar
  9. —————..Agra Univ. Jour. of Research, 1952,1, 185.Google Scholar

Copyright information

© Indian Academy of Sciences 1955

Authors and Affiliations

  • Sunita Inderjit Singh
    • 1
  • Inderjit Singh
    • 1
  1. 1.From the Physiology DepartmentMedical CollegeAgra

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