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Part XII. Synthesis and fungistatic activity of 5: 6- and 5:8-quinoline quinone
  • B. Harinath Babu
  • N. V. Subba Rao


A few 5:6- and 5:8-quinoline quinones have been synthesised by oxidising the corresponding aminohydroxy and diaminoquinolines. The required aminohydroxy quinolines could be prepared by nitrosation of hydroxy quinolines and subsequent reduction. Coupling the monoamino quinolines with diazotised sulphanilic acid and reduction afforded the diamino quinolines. 6:7-Dichloro- and 6:7-dibromo-5:8-quinoline quinones exhibited fungistatic activity nearly equal to that of 2:3-dichloro-1:4-naphthoquinone.


Quinone Quinoline Hydroxy Quinoline Sodium Dithionite Fungistatic Activity 
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Copyright information

© Indian Academy of Sciences 1968

Authors and Affiliations

  • B. Harinath Babu
    • 1
  • N. V. Subba Rao
    • 1
  1. 1.Department of ChemistryOsmania UniversityHyderabad-7

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