Synthetical experiments in the chromone group

Part XXIX. A method for the reduction of 5:7-dihydroxyflavones to 5-hydroxyflavones
  • V. Ramanathan
  • K. Venkataraman


A general method for the preparation of 5-hydroxyflavone and its derivatives from the corresponding 5:7-dihydroxyflavones by the action of Raney nickel on the 7-tosyloxy derivatives is described. Thus chrysin has been converted into 5-hydroxyflavone, and galangin 3-methyl ether to 5-hydroxy-3-methoxyflavone.


Chrysin Raney Nickel Anhydrous Potassium Carbonate Selenium Dioxide Caustic Potash 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Karrer and Schwab..Helv. Chim. Acta, 1941,24, 297.CrossRefGoogle Scholar
  2. 2.
    Sugasawa ..J. Chem. Soc., 1934, 1483.Google Scholar
  3. 3.
    Baker ..Ibid., 1934, 1953.Google Scholar
  4. 3a.
    See also Rajagopalan, Rao and SeshadriProc. Ind. Acad. Sci., 1947,25A, 432.Google Scholar
  5. 3b.
    Iyer and Venkataraman.., 1953,37A, 629.Google Scholar
  6. 4.
    Seshadri and Venkateswarlu.., 1947,26A, 189.Google Scholar
  7. 5.
    Kenner and Murray ..J. Chem. Soc., 1949, S178.Google Scholar
  8. 6.
    Ramanathan and Venkataraman..Curr. Sci., 1952,21, 283.Google Scholar
  9. 7.
    Robinson and Venkataraman ..J. Chem. Soc., 1926, 2344.Google Scholar
  10. 8.
    Rao, Rao and Seshadri..Proc. Ind. Acad. Sci., 1947,25A, 427.Google Scholar
  11. 9.
    Kalff and Robinson..J. Chem. Soc., 1925,127, 181.Google Scholar
  12. 10.
    Wilson..J. Am. Chem. Soc., 1939,61, 2304.Google Scholar
  13. 11.
    Mahal, Rai and Venkataraman ..J. Chem. Soc., 1935, 866.Google Scholar
  14. 12.
    Karmarkar, Shah and VenkataramanProc. Ind. Acad. Sci., 1952,36A, 552.Google Scholar
  15. 13.
    Seshadri, Varadarajan and Venkateswarlu, 1950,32A, 250.Google Scholar

Copyright information

© Indian Academy of Sciences 1953

Authors and Affiliations

  • V. Ramanathan
    • 1
  • K. Venkataraman
    • 1
  1. 1.Department of Chemical TechnologyUniversity of BombayIndia

Personalised recommendations