Netherlands Journal of Plant Pathology

, Volume 83, Supplement 1, pp 253–260 | Cite as

Mechanism of polyoxin resistance

  • T. Misato
  • K. Kakiki
  • M. Hori
Resistance to Systemic Fungicides


In polyoxin-resistant strains of Alternaria kikuchiana, the synthesis of cell-wall chitin was scarcely inhibited by polyoxin B, although chitin synthetase preparations of them showed a level of polyoxin sensitivity similar to those of sensitive strains. A decrease of14C-labelled polyoxin uptake was correlated with an increased level of polyoxin resistance in various strains. The amount of14C-polyoxin A or3H-polyoxin A accumulated in a highly resistant strain was less than 10% of that in a sensitive strain. These results indicate that resistant strains have a reduced capacity to take up polyoxin A or B.


Chitin Chitinase Resistant Strain GlcNAc Chitin Synthesis 
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Copyright information

© Koninklijke Nederlandse Planteziektenkundige Vereniging 1977

Authors and Affiliations

  • T. Misato
    • 1
  • K. Kakiki
    • 1
  • M. Hori
    • 2
  1. 1.The Institute of Physical and Chemical ResearchSaitamaJapan
  2. 2.Kaken Chemical Co., LtdTokyoJapan

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