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Les lymphomes de l’intestin Aspects anatomo-pathologiques

Intestinal lymphomas Anatomo-pathological features

  • Lymphomes du Tube Digestif
  • Published:
Acta Endoscopica

Résumé

Les lymphomes intestinaux représentent en Occident 30% des lymphomes primitifs du tube digestif et sont parmi les cancers les plus fréquents de l’intestin grêle. Les lymphomes du tube digestif ont suscité de nombreux travaux et sont à la base du concept du «Mucosa Associated Lymphoma Tissue» ou MALT et de la nouvelle classification des lymphomes du tube digestif proposés par Isaacson. Au niveau de l’intestin, deux tiers des lymphomes ont un phénotype B et correspondent le plus souvent à des lymphomes du MALT qu’il faudra différencier de la polypose lymphomateuse ou lymphome du manteau beaucoup plus rare mais de pronostic très péjoratif. Les autres lymphomes intestinaux ont un phénotype T et correspondent essentiellement aux lymphomes associés à la maladie caeliaque.

Summary

Intestinal lymphomas account for 30% of primary gut lymphomas in western countries and are among the most common cancers of the small bowel. Gut lymphomas have been extensively studied and constitutte the basis of the new concept of Mucosa Associated Lymphoid Tissue or MALT and of the new classification of primary gastrointestinal lymphomas proposed by Isaacson. For the intestine, two thirds of lymphomas have a B-cell phenotype and most often correspond to MALT lymphoma and must be differentiated from multiple lymphoma polyposis or mantle cell lymphoma, rarer but with a poorer prognosis. The other intestinal lymphomas have a T-cell phenotype and essentially correspond to enteropathy-associated lymphomas.

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De Mascarel, A., Belleannee, G. & Parrens, M. Les lymphomes de l’intestin Aspects anatomo-pathologiques. Acta Endosc 28, 547–561 (1998). https://doi.org/10.1007/BF03036206

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