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Biological Trace Element Research

, Volume 29, Issue 1, pp 51–75 | Cite as

Minor and trace elements in human milk from Guatemala, Hungary, Nigeria, Philippines, Sweden, and Zaire

Results from a WHO/IAEA joint project
  • Robert M. Parr
  • Edouard M. DeMaeyer
  • Venkatesh G. Iyengar
  • Anthony R. Byrne
  • Gordon F. Kirkbright
  • Gerhard Schöch
  • L. Niinistö
  • Oscar Pineda
  • H. L. Vis
  • Yngve Hofvander
  • A. Omololu
Article

Abstract

Concentrations of As, Ca, Cd, Cl, Co, Cr, Cu, F, Fe, Hg, I, K, Mg, Mn, Mo, Na, Ni, P, Pb, Sb, Se, Sn, V, and Zn were determined in human whole milk samples from Guatemala, Hungary, Nigeria, Phillippines, Sweden, and Zaire; in most of these countries, three groups of subjects representing different socioeconomic conditions were studied. Analytical quality control was a primary consideration throughout. The analytical techniques used were atomic absorption spectrophotometry, atomic emission spectrometry with an inductively coupled plasma, colorimetry, electrochemistry, using an ionselective electrode and neutron activation analysis.

The differences between median concentrations of Ca, Cl, Mg, K, Na, and P (minor elements) were lower than 20% among the six countries. Among trace elements, concentrations observed in Filipino milk for As, Cd, Co, Cr, Cu, F, Fe, Mn, Mo, Ni, Pb, Sb, Se, and V were higher than for milk samples from other countries. The remaining five countries showed a mixed picture of high and low values. In the case of at least some elements, such as, F, I, Hg, Mn, Pb, and Se, the environment appears to play a major role in determining their concentrations in human milk. The nutritional status of the mother, as reflected by her socioeconomic status, does not appear to influence significantly the breast milk concentrations of minor and trace elements.

Significant differences exist between the actual daily intakes observed in this study and current dietary recommendations made by, for example, WHO and the US National Academy of Sciences. These differences are particularly large (an order of magnitude or more!) for Cr, F, Fe, Mn, and Mo; for other elements, such as, Ca, Cu, Mg, P, and Zn, they amount to at least a factor 2. In the opinion of the present authors, these findings point to the need for a possible reassessment of the dietary requirements of young infants, with respect to minor and trace elements, particularly for the elements Ca, Cr, Cu, F, Fe, Mg, Mn, Mo, P, and Zn.

Index Entries

Human milk elemental composition trace elements geographic comparison geochemical influence lactation infant nutrition pediatric mineral nutrition developing countries urban rural 

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Copyright information

© Humana Press Inc. 1991

Authors and Affiliations

  • Robert M. Parr
    • 1
  • Edouard M. DeMaeyer
    • 2
  • Venkatesh G. Iyengar
    • 3
    • 4
  • Anthony R. Byrne
    • 5
  • Gordon F. Kirkbright
    • 6
  • Gerhard Schöch
    • 7
  • L. Niinistö
    • 8
  • Oscar Pineda
    • 9
  • H. L. Vis
    • 10
  • Yngve Hofvander
    • 11
  • A. Omololu
    • 12
  1. 1.International Atomic Energy AgencyViennaAustria
  2. 2.World Health OrganizationGeneva 27Switzerland
  3. 3.Institute of MedicineNuclear Research Center JuelichJeulichFRG
  4. 4.National Institute of Standards and TechnologyCenter for Analytical ChemistryGaithersburg
  5. 5.Nuclear Chemistry DepartmentJozef Stefan InstituteLjubljanaYugoslavia
  6. 6.Department of Instrumentation and Analytical ScienceUMISTManchesterUK
  7. 7.Forschungsinstitut fuer KinderernaehrungDortmundFRG
  8. 8.Laboratory of Inorganic and Analytical ChemistryHelsinki University of TechnologyEspooFinland
  9. 9.Institute of Nutrition for Central America and Panama (INCAP)Guatemala CityGuatemala
  10. 10.Department of PediatricsFree UniversityBrusselsBelgium
  11. 11.Department of PediatricsUniversity HospitalUppsalaSweden
  12. 12.College of MedicineUniversity of IbadanIbadanNigeria

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